载入高分子有机相增强磷酸钙骨水泥力学性能的方法  

Mechanical Reinforcement Strategy of Calcium Phosphate Cements by Loading Polymers

作　　者：林孙忠[1] 屈树新[2] 薛继鑫[1] 林婵娟[1] 翁杰[2] LIN Sunzhong;QU Shuxin;XUE Jixin;LIN Chanjuan;WENG Jie(Clinical Engineering Department, The Second A？liated Hospital, Yuying Children＇s Hospital of Wenzhou Medical College, Wenzhou, 3250002;Key Lab of Advanced Technologies of Materials of Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, 61003)

机构地区：[1]温州医科大学附属第二医院育英儿童医院临床工程处,温州市325000 [2]西南交通大学材料科学与工程学院材料先进技术教育部重点实验室,成都市610031

出　　处：《中国医疗器械杂志》2018年第3期198-201,共4页Chinese Journal of Medical Instrumentation

基　　金：国家自然科学基金青年科学基金项目(81401798)

摘　　要：磷酸钙骨水泥(CPC)具有良好的生物活性,但CPC是脆性材料,抗压强度和弯曲强度低,目前只应用在非承重部位的骨缺损修复。该文综述了近年来载入各类高分子有机相来增强CPC力学性能的研究,归纳总结了载入纤维、高分子微球,制备双相固化CPC这几种增强力学性能的方法。分析总结这些增强方式的优缺点及其原理,为进一步改进、制备力学性能优异、符合承重部位的骨缺损修复要求的CPC奠定基础。Calcium phosphate cement（CPC） is well known for the excellent bioactivity and biocompatibility, however, CPC has been used only for the repair of non-load bearing bone defects due to its brittle nature and low flexural strength. Polymer reinforced CPC has been considered as one of the most effective strategies for mechanical reinforcement. This paper summarizes various kinds of polymers loaded CPC： fiber reinforcement, microsphere reinforcement and dual setting cements. It is aimed to analyze the advantages, disadvantages and principles of the polymers reinforced CPC, and so as to lay a foundation for the further research of improving and manufacturing the CPC with ideal mechanical properties.

关 键 词：磷酸钙骨水泥 力学增强 纤维增强 微球增强 双相磷酸钙骨水泥 

分 类 号：R318.08[医药卫生—生物医学工程] TB33[医药卫生—基础医学]