蒙药那如-3血清指纹图谱研究  

The Study on Serum Fingerprint of Traditional Mongolian Medicine-Naru-3

作　　者：布林白乙拉 何桂松 胡弟 高秋红 王经韵[3] 何冰[2] Bulinbaiyila;He Guisong;Hu Di;Gao Qiuhong;Wang Jingyun;He Bing(Department of Orthopedics;Panyu Hospita;The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 511447, Chin;2. College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, Chin;3. Guangdong General Hospital, Guangzhou 510080, China)

机构地区：[1]广州医科大学附属第二医院番禺院区骨科,广东广州511447 [2]广东药科大学药科学院,广东广州510006 [3]广东省人民医院国家临床药物实验机构办公室,广东广州510080

出　　处：《亚太传统医药》2018年第5期20-22,共3页Asia-Pacific Traditional Medicine

基　　金：广东省科学技术厅广东省中医药科学院联合科研专项(粤科社字[2013]102号);广东省大学生创新训练项目(201610573039)

摘　　要：目的:通过研究蒙药那如-3血清指纹图谱,进一步了解其药效物质基础。方法 :采用高效液相色谱法(HPLC),建立蒙药那如-3大鼠灌胃后血清指纹图谱,分析其血清中的有效成分。结果:在蒙药那如-3的含药血清中发现3个入血成分:乌头碱、胡椒碱和没食子酸。结论 :乌头碱、胡椒碱和没食子酸为蒙药那如-3的主要入血成分,是蒙药那如-3的有效成分。Objective：To investigate the bioactive constituent of traditional Mongolian medicine-Naru-3,the method of Serum Fingerprints were established.Methods：Serum fingerprints of HPLC were adopted to determine the components of traditional Mongolian medicine-Naru-3 absorbed into blood.Results：Three components absorbed into blood were detected by HPLC,aconitine,piperine and gallic acid.Conclusion：Conclusion：Aconitine,piperine and gallic acid were possible the bioactive components absorbed into blood.

关 键 词：蒙药那如-3 高效液相色谱 血清指纹图谱 

分 类 号：R284.2[医药卫生—中药学]