红细胞分布宽度与急性胸痛患者短期预后相关性分析  

Correlation Analysis between Red Cell Volume Distribution Width and Short-term Prognosis in Patients with Acute Chest

作　　者：刘文德 黄振华[2] 刘志豪[2] 陈职堂 廖瑾莉[2] 周锦华 徐嘉[2] 熊艳[2] 詹红[2] LIU Wen-de1, LIU Zhi-hao2, HUANG Zhen-hua2, CHEN Zhi-tang1, LIAO Ji-li2, ZHOU Jin-hua1, XU Jia2, XIONG Yan2, ZHAN Hong2(1. The Department of Emergency, The Huidong People＇s Hospital, huizhou, 516300; 2. The Department of Emergency, The First Affiliated Hospital of Sun Yat Sen University, Guangzhou)

机构地区：[1]广东省惠州市惠东县人民医院急诊科,516300 [2]中山大学附属第一医院急诊科

出　　处：《岭南急诊医学杂志》2018年第2期108-110,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨红细胞分布宽度(red cell volume distribution width,RDW)与急性胸痛短期(30天)预后的相关性。方法:连续收集中山大学附属第一医院急诊科2016年1月1日至2017年12月31日因"胸痛、胸闷"为主诉就诊的495例患者资料,根据是否发生重大心血管不良事件(major adverse cardiovascular events,MACE)分为MACE组25例和对照组470例。结果:MACE组和对照组临床基线资料比较发现MACE组患者年龄(73.88±13.0岁),高血压患病率(64%),RDW(0.143±0.025)、HEART评分(6.40±2.0)、GRACE评分(148.40±34.8)均高于对照组患者,两组比较具有明显统计学差异(P<0.01);RDW与HAERT评分、GRACE评分显著相关(r=0.188,P<0.05;r=0.191,P<0.05)。单独RDW预测急性胸痛患者30天MACE曲线下面积仅有0.592,联合HEART评分及GRACE评分预测急性胸痛患者30天MACE曲线下面积分别为0.747、0.751,预测效果均高于单一指标。结论:RDW可预测急性胸痛短期MACE,联合HEART、GRACE评分预测MACE会更准确。Objective： To investigate the relationship between red cell volume distribution width and short-term prognosis （30 day） in patients with acute chest. Methods： 495 patients with acute chest pain continuously in Emergency Department of the First Affiliated Hospital, the Sun Yat-Sen University from January 1, 2016-December 3l, 2016 were collected. According to the occurrence of major adverse cardiovascular events （MACE） , 25 patients were divided into MACE group and 470 patients in control group. Results： Compared with control group, age（73.88±13.0）years, hy- pertension prevalence （64%） , red cell volume distribution width （RDW） （0.143±0.025 ） , HEART score （6.40±2.0） , GRACE score （148.40±34.8） in MACE group was significantly higher than those in control group （P 〈 0.01 ） ; There were significant correction between RDW and HEART score or GRACE score （r=0.188, P〈0.05 ; r=0.191, P〈0.05 respectively） ; The predictions of RDW on 30-day MACE of acute chest pain were shown in Figure 1 and Table 3. The predictive area under ROC curve of RDW for 30-day MACE of acute chest pain was 0.592. However, the predictive area under ROC curve of RDW combined HEART score or GRACE score for 30-day MACE of acute chest pain was 0.747, 0.751, respectively, and the effect of prediction was better than single indictor. Conclusion ： The RDW was a useful predictor to the occurrence of 30-day cardiovascular adverse events in acute chest pain patients. It may be more accurate if RDW combine HEART score or GRACE score for predicting occurrence of 30-day MACE.

关 键 词：红细胞分布宽度 急性胸痛 短期预后 相关性分析 

分 类 号：R54[医药卫生—心血管疾病]