消积散结止痛膏治疗慢性肝病胁痛疗效观察  

Efficacy Observation of Xiaoji Sanjie Zhitong Ointment in Treating for Pain in Hypochondrium with Liver Disease

作　　者：娄静[1] 王菲[1] 侯留法[1] 赵雷[1] LOU Jing;WANG Fei;HOU Liufa;ZHAO Lei(The Affiliated Hospital to Henan Academy of Traditional Chinese Medicine,Zhengzhon Henan China 45000)

机构地区：[1]河南省中医药研究院附属医院,河南郑州450000

出　　处：《中医学报》2018年第5期852-855,共4页Acta Chinese Medicine

基　　金：河南省中医管理局学科带头人专项课题项目(2013ZY03038)

摘　　要：目的:观察消积散结止痛膏治疗慢性肝病胁痛的临床疗效。方法:将142例肝病胁痛患者按随机数字表法分为对照组70例和治疗组72例,治疗组在常规保肝降酶及对症治疗基础上,加用消积散结止痛膏外敷肝区,每天1贴,每次6~8 h。对照组在常规对症治疗基础上,加用消积散结止痛膏模拟剂,外敷肝区,每天1贴,每次6~8 h。4周为1个疗程,共治疗1个疗程。观察两组患者治疗前后疼痛程度、门静脉系统血流动力学变化和生活质量改善情况。结果:治疗后治疗组有效率为97.2%,明显高于对照组的37.1%,差异有统计学意义(P<0.01)。治疗后治疗组门静脉内径、脾静脉内径较治疗前均明显缩小,差异均有统计学意义(P<0.01);且治疗后两组比较,差异均有统计学意义(P<0.01)。治疗后门静脉和脾静脉平均流速、流量均明显降低,与对照组治疗后比较,差异均有统计学意义(P<0.01)。治疗后治疗组腹部症状、乏力、焦虑等症状均有改善,两组比较,差异均有统计学意义(P<0.01)。结论:消积散结止痛膏治疗慢性肝病胁痛疗效显著,能缩小门静脉内径和脾静脉内径,门静脉和脾静脉平均流速、流量均明显降低,腹部症状、乏力、焦虑等症状均有改善。Objective： To observe the clinical efficacy of Xiaoji Sanjie Zhitong Ointment in treating for pain in hypochondrium with Liver disease. Methods： One hundred and forty-two cases of liver disease with hypochondriac pain were randomly divided into control group and treatment group. Seventy cases and treatment group were treated with conventional Xiaogan Sanjie Zhitong Ointment in addition to the routine hepatoprotective enzyme therapy and symptomatic treatment,with 1 sticker per day for 6-8 hours each time. In the control group,based on the conventional symptomatic treatment,a Xiaoji Sanjie Zhitong Ointment mimic was added,with 1 sticker per day for 6-8 hours each time. 4 weeks was one course of treatment,and the observation lasted one course of treatment. Before and after treatment,the two groups of patients were assessed in pain,hemodynamic changes in the portal venous system and quality of life. Results： The effective rate of the treatment group after treatment was 97. 2%,which was significantly higher than that(37. 1%） of the control group(P 〈 0. 01）. After treatment,the diameter of portal vein and the diameter of splenic vein in the treatment group were significantly reduced compared with those before treatment(P 〈 0. 01）. The difference between the two groups after treatment was statistically significant(P 〈 0. 01）. After treatment,the mean flow velocity and flow rate of portal vein and splenic vein were significantly reduced,and there was a statistically significant difference compared with the control group after treatment(P 〈 0. 01）. After treatment,symptoms like abdominal symptoms,fatigue,and anxiety were improved in the treatment group. There was a statistically significant difference between the two groups(P 〈 0. 01）. Conclusion： Xiaoji Sanjie Zhitong Ointment has a remarkable curative efficacy in treating for hypochondriac pain with Liver disease. It can reduce the inner diameter of portal vein and the diameter of splenic vein. The mean flow velocity and flow rate of portal

关 键 词：慢性肝病胁痛 消积散结止痛 生活质量 中医药疗法 中西医结合 

分 类 号：R259[医药卫生—中西医结合]