威海地区腹泻致病菌及药敏分析  被引量:4

Analysis of diarrhea pathogenic bacteria and drug sensitivity in Weihai

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作  者:刘振波 卞志伟 高娟娟 黄君君 LIU Zhen-bo, BIAN Zhi-wei, GAO Juan-juan, HUANG Jun-jun(Rongcheng Entry-Exit Inspection and Quarantine Bureau, Rongcheng, Shandong 264300, Chin)

机构地区:[1]荣成出入境检验检疫局,山东荣成264300 [2]烟台出入境检验检疫局

出  处:《中国国境卫生检疫杂志》2018年第2期84-86,共3页Chinese Journal of Frontier Health and Quarantine

摘  要:目的调查威海地区腹泻患者的致病菌及其药物敏感性,指导国际旅行者用药。方法收集2016—2017年威海市立医院门诊及住院腹泻患者粪便样本2 400份,接种于肠道致病菌选择培养基,对可疑菌落进行纯化,利用微生物鉴定及药敏分析系统鉴定致病菌的种类及其对阿米卡星、头孢噻肟、复方新诺明、庆大霉素、诺氟沙星、头孢唑啉、氨苄西林、环丙沙星8种药物的敏感性。结果在2 400份粪便样本中,有1 105份检出致病菌,其中以弧菌属细菌最多,共837份(75.75%)。其次是志贺菌属,共148份(13.39%);大肠埃希菌属、气单胞菌属、假单胞菌属、沙门菌属及耶尔森菌属合计120份(10.86%)。各菌属致病菌对8种药物的敏感率平均值由高到低依次为阿米卡星95.30%、头孢噻肟89.76%、庆大霉素76.98%、头孢唑啉68.91%、环丙沙星55.79%、复方新诺明55.19%、诺氟沙星33.97%、氨苄西林21.54%。结论威海地区腹泻致病菌主要是弧菌属细菌,大部分致病菌对阿米卡星和头孢噻肟敏感,可作为治疗的首选药物。Objective To investigate the pathogenic bacteria and its drug susceptibility of diarrhea patients in Weihai city,and to guide the medication for the international travelers. Methods A total of 2 400 diarrhea fecal samples were collected from outpatient and inpatient hospitalized patients at Weihai Municipal Hospital,2016-2017. The samples were inoculated on the selection medium of intestinal pathogenic bacteria,and the suspicious colonies were purified. The bacterial identification and the pathogenic bacteria drug sensitivity test were performed by microbial identification and drug sensitivity analyze system. Eight kinds of drug including Amikacin(AK),Cefotaxime(CTX),Compound Sulfame thoxazole(SXT),Gentamycin sulfate(CN),Norfloxacin(NOR),Cefazolin sodium(KZ),Ampicillin(AMP),Ciprofloxacin hydrochloride(CIP) were used for the test. Results In the total 2 400 samples,1 105 were found pathogenic bacteria,837(75.75%) were Vibrio,148(13.39%) were Shigella,120(10.86%) were Escherichia,Aeromonas,Pseudomonasa,Salmonella and Yersinia. The average drug sensitivity from high to low was AK 95.30%,CTX 89.76%,CN 76.98%,KZ 68.91%,CIP 55.79%,SXT 55.19%,NOR 33.97%,AMP 21.54%. Conclusion The major diarrhea pathogenic bacteria was Vibrio in Weihai city. Most of the diarrhea pathogens were sensitive to AK and CTX. AK and CTX could be used as the first choice for diarrhea patient.

关 键 词:腹泻 细菌 抗生素 药敏 

分 类 号:R183.4[医药卫生—流行病学]

 

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