51283例住院患者与献血者Rh血型分布和分析  

Distribution of Rh blood group in 51283 cases of inpatients and voluntary blood donors

作　　者：马婷[1] 杨江存[1] 宋耀军[1] 王文华[1] 谢昕昕[1] 陈萍[1] 杨颖群 常靖妍 王妙妮 MA Ting, YANG Jiangcun, SONG Yaojun, WANG Wenhua, XIE Xinxin, CHEN Ping, YANG Yingqun, CHANG Jingyan, WANG Miaoni(Department of Transfusion Medicine, Shaanxi Provincial People＇s Hospital, Xi＇an 710068, Chin)

机构地区：[1]陕西省人民医院输血科,陕西西安710068

出　　处：《细胞与分子免疫学杂志》2018年第1期70-74,共5页Chinese Journal of Cellular and Molecular Immunology

摘　　要：目的分析51 283例住院患者与无偿献血者Rh血型抗原分布特征。方法对31 818名住院患者及19 465名无偿献血者通过微柱凝胶方法进行Rh血型D、E、e、C、c抗原进行检测。结果住院患者与献血者Rh血型分布频率不同,住院患者与献血者Rh血型分布构成比主要为DCCee及DCcEe两种,住院患者为41.64%、36.58%,献血者为41.11%、37.11%;不同ABO血型住院患者及献血者Rh血型分布不同;Rh D阳性患者主要Rh血型为CcEe(36.58%)及CCee(41.64%),RhD阴性患者Rh血型主要为ccee(54.30%)及Ccee(30.86%);不同科室患者仅血液科与总住院患者Rh血型分布不同,与文献记录的合肥、广州、南宁与西安地区献血者Rh血型分布有显著差异,而咸阳地区与西安地区差异不明显。结论不同人群、科室、地区等Rh血型分布特征不同,Rh血型检测对临床安全合理输血具有重要意义。Objective To investigate the distribution characteristics of Rh blood group in 51 283 cases of inpatients and voluntary blood donors. Methods Micro-column gel test was used to detect RhD, RhE, Rhe, RhC, Rhc antigen in 31 818 cases of hospitalized patients and 19 465 cases of voluntary blood donors. Results There were significant differences in Rh blood type distribution between inpatients and voluntary blood donors. The mainly phenotype of Rh blood group in the inpatients were DCCee （41.64%） and DCcEe （ 36.58% ）, and Rh blood type in voluntary blood donors were DCCee （41.11%） and DCcEe （37.11%）. There were noticeable differences in Rh blood group and ABO phenotype between inpatients and voluntary blood donors. The mainly phenotype of the RhD positive patients were CcEe （36.58%） and GCee （41.64%）. However, the mainly phenotype of RhD negative patients were ccee （54.30%） and Ccee （30.86%）. Additionally, obvious difference of Rh blood group was seen between patients in haematology department and all patients. The voluntary blood donors from different areas including Hefei, Guangzhou, Nanning and Xi＇an showed significant different Rh blood group distribution. On the contrary, no obvious difference of Rh blood group was found between Xianyang and Xi＇an. Conclusion The differences of Rh blood group distribution have been found in different populations, departments and areas, which make it extremely important to detect Rh blood group in clinical transfusion.

关 键 词：输血安全 RH血型 分布频率 

分 类 号：R457.11[医药卫生—治疗学]