多囊卵巢综合征患者不良妊娠结局研究现状  

Progress of adverse pregnancy outcomes in polycystic ovary syndrome patients

作　　者：黄凤 周全[1] 毛巧玲 黄分 郑文斐[1] 佐满珍[1] Huang Feng;Zhou Quan;Mao Qiaoling;Huang Fen;Zheng Wenfei;Zuo Manzhen(Department of Obstetrics and Gynecology, The First People＇s Hospital of Yichang, China Three Gorges University, Yichang 443000, Chin)

机构地区：[1]三峡大学人民医院/宜昌市第一人民医院妇产科,湖北省宜昌443000

出　　处：《中国医师杂志》2018年第5期793-796,共4页Journal of Chinese Physician

基　　金：国家自然科学基金(81401187)~~

摘　　要：多囊卵巢综合征(PCOS)是导致育龄期妇女内分泌紊乱及不孕不育的常见病。大量研究证明PCOS发病机制与患者自身存在的胰岛素抵抗、高雄激素血症和高体重指数有关。目前,关于PCOS患者受孕方法及减少多胎妊娠的研究有了很大的进展,但对其受孕后导致的不良妊娠结局的研究相对较少。因此,本研究借助循证医学证据分别对孕产妇并发症:妊娠期高血压疾病、妊娠期糖尿病、流产和早产不良结局作一综述。了解PCOS病理生理变化及影响其发生发展的高危因素,探讨PCOS患者孕前孕期管理策略,为临床工作中行早期预防及干预提供参考依据。Polycystic ovary syndrome （PCOS） is a common disease that lead to endocrine disorders and infertility in women of child-bearing age. A large number of studies have shown that the pathogenesis of PCOS is related to insulin resistance （IR） , hyperandrogenism and high body mass index. At present, remarkable progress has been made in the study of conception methods and the reduction of multiple pregnancies in PCOS patients. However, there is relatively little research on the adverse pregnancy outcomes after conception. Therefore, this study will use evidence-based medicine to make a review of complications in maternal. For instance, pregnancy-induced hypertension syndrome （PIH）, gestational diabetes mellitus （GDM） , miscarriage, premature delivery and so on. This study provides an overall basis for early prevention and intervention in clinical work through discussing the pathophysiology of PCOS, the risk factors of its occurrence and development, and the management strategies of pre-pregnancy and gestation period.

关 键 词：多囊卵巢综合征 妊娠并发症 妊娠结局 综述 

分 类 号：R711.75[医药卫生—妇产科学]