支气管哮喘-慢性阻塞性肺疾病重叠的研究进展  

Research progress of asthma and chronic obstructive pulmonary disease overlap

作　　者：冯颖[1] FENG Ying(Department of Medicine, Tianjin Prevention and Treatment Center of Occupational Diseases （Workers＇ Hospital）, Tianjin 300020, Chin)

机构地区：[1]天津市职业病防治院(工人医院)综合内科,天津300020

出　　处：《中国城乡企业卫生》2018年第5期37-39,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：支气管哮喘和慢性阻塞性肺疾病(COPD)同属慢性气道炎性疾病,两者各具特征。典型病例不难区分,但有的患者既有哮喘的特征,亦有COPD的特征。基于上述现象,2017年GINA建议用哮喘-慢性阻塞性肺疾病重叠(ACO)来描述这一现象。相对于哮喘和COPD,ACO的患者发作更为频繁,增加住院次数,影响患者生活质量,缩短患者寿命。因此正确认识ACO,予以正确诊断和治疗意义重大。本文从流行病学、病因、病理生理学特征、症状特征、辅助检查、诊断标准及治疗几个方面,对ACO近几年的临床研究进展做一总结。Asthma and chronic obstructive pulmonary disease are chronic inflammatory diseases of the airway,but they have different characteristics. In a typical case,it is not difficult to distinguish. But some patients have the both clinical characteristics of asthma and COPD. Based on this phenomenon,GINA proposed using Asthma-COPD overlap（ACO） to describe it in 2017. ACO has more frequent attack,more hospitalization,poorer quality of life and shorter life span than asthma and COPD. Therefore,the correct understanding,diagnosis and treatment of ACO have great significance. This article aims to sum up the progress of the recent clinical studies of ACO from the aspects of epidemiology,etiology,pathology and physiology characteristics,symptom characteristics,accessory examination,diagnostics criteria and treatment.

关 键 词：哮喘 慢性阻塞性肺疾病 哮喘-慢性阻塞性肺疾病重叠 

分 类 号：R373.33[医药卫生—病原生物学]