多光谱照射治疗中老年维生素D缺乏骨质疏松症临床观察  

Clinical Observation on Multi Spectral Irradiation for Middle and Old Aged Osteoporosis Patients with Vitamin D Deficiency

作　　者：邢军[1] 马振芳 王亚辉[1] 茹意 芦剑锋 严丽[2] 安经克[2] XING Jun;MA Zhenfang;WANG Yahui;RU Yi;LU Jianfengz;YAN Li;AN Jingke(The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China;Hebei General Hospital, Shijiazhuang, Hebei 050051, China)

机构地区：[1]河北医科大学第一医院,河北石家庄050031 [2]河北省人民医院,河北石家庄050051

出　　处：《康复学报》2018年第2期18-22,共5页Rehabilitation Medicine

基　　金：河北省科技计划项目(16277735D)

摘　　要：目的:观察多光谱照射治疗中老年维生素D缺乏骨质疏松症的临床疗效。方法:将102例维生素D缺乏的中老年骨质疏松症患者按照随机数字表法分为治疗组和对照组,每组各51例。治疗组采用ATWLYY-Ⅰ型多波段光谱治疗仪照射患者脊柱、腹部及疼痛关节部位,对照组接受自然光照射治疗。每天照射2个部位,持续照射30 d。治疗前后采用视觉模拟评分法(VAS)评估2组患者骨疼程度,检测其体内骨密度BMD值及维生素D、血钙、血磷、碱性磷酸酶的含量,观察血糖、总胆固醇、肌酐、谷丙转氨酶、谷草转氨酶等安全性指标的变化。结果:治疗30 d后,治疗组骨疼VAS评分及碱性磷酸酶含量较治疗前明显降低(P<0.05),骨密度BMD值及维生素D含量明显升高(P<0.05);2组治疗前后血糖、总胆固醇、肌酐、谷丙转氨酶、谷草转氨酶含量比较,差异无统计学意义。结论:多光谱照射治疗中老年维生素D缺乏骨质疏松症有较好效果。Objective：To observe the clinical effect of multi spectral irradiation on middle and old aged osteoporosis patients with vitamin D deficiency. Methods：102 middle and old aged osteoporosis patients with vitamin D deficiency were randomly assigned to the treatment group and control group, and 51 patients were in each group. The treatment group received the irradiation of spinal column, abdomen and pain joints by using ATWL-YY-Ⅰ type production of multi band spectral instrument, and the control group received natural illumination. Two parts were irradiated per day, and the irradiation lasted for 30 days. The visual analog scale（VAS）were used to assess the extent of bone pain, bone mineral density（BMD） value and levels of vitamin D, blood calcium, blood phosphorus and alkaline phosphatase in patient＇s body were detected, and the changes of safety indexes such as blood glucose, total cholesterol, creatinine, glutamate pyruvate transaminase and glutamic-oxal（o）acetic transaminase were observed. Results ：After 30 day＇s therapy, the bone pain VAS score and alkaline phosphatase level were decreased compared with those before treatment（P〈0.05）, and the BMD value and vitamin D level were increased compared with those before treatment（P〈0.05）. There was no significant difference in levels of blood glucose, total cholesterol, creatinine, glutamate pyruvate transaminase and glutamic-oxal（o）acetic transaminase of two groups before and after treatment. Conclusion：Multi spectral irradiation therapy has a good effect on middle and old aged osteoporosis patients with vitamin D deficiency.

关 键 词：骨质疏松 维生素D缺乏 多波段光谱 经皮照射 VAS评分 骨密度 血钙 血磷 碱性磷酸酶 

分 类 号：R580[医药卫生—内分泌]