中药片剂成型质量影响因素研究现状及问题分析  

Current situations and problem analysis of influencing factors of traditional Chinese medicine tablets on forming quality

作　　者：李延年[1] 伍振峰 万娜 李远辉[1] 李慧婷[1] 杨明[1,2] LI Yan-nian;WU Zhen-feng;WAN Na;LI Yuan-hui;LI Hui-ting;YANG Ming(College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine under Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China)

机构地区：[1]成都中医药大学药学院,四川成都610072 [2]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004

出　　处：《中国中药杂志》2018年第8期1547-1553,共7页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81673613);江西省科技条件平台建设项目(20142BCD40037)

摘　　要：片剂的压缩成型是一个复杂的过程,也是中药片剂制备过程的关键操作单元,因此,全面研究中药片剂成型过程中的影响因素具有重要意义。该文通过查阅片剂成型的相关文献,介绍了片剂成型质量的评价方式,分析了物料粉体学性质、辅料及制备工艺对中药片剂成型质量的影响,并对中药片剂成型研究过程中存在的问题进行了探讨,以期为提高中药片剂成型质量提供参考。The compressibility of tablets is the essential operating unit during the preparation of traditional Chinese medicine tablets,as well as a complicated process. Therefore,it is of great significance to comprehensively study the influencing factors on the formation process. This paper aimed to review the evaluation methods for the tablet forming quality and highlight the effects of material powder properties,excipients and preparation technology on the quality of traditional Chinese medicine tablets on the basis of relevant literatures. Furthermore,the common problems in tablet forming process are also analyzed to provide useful references for the development of tablet forming quality of traditional Chinese medicines.

关 键 词：中药片剂 成型质量 综述 粉体学性质 辅料 制备工艺 

分 类 号：R283.6[医药卫生—中药学]