药用百合正源考证研究  

Textual research on origin and genuine of Lilii Bulbus

作　　者：王昌华[1] 舒抒[1] 银福军[1] 赵纪峰[1] 张植玮[1] 刘翔[1] 詹志来 WANG Chang-hua;SHU Shu;YIN Fu-jun;ZHAO Ji-feng;ZHANG Zhi-wei;LIU Xiang;ZHAN Zhi-lai(Chongqing Academy of Chinese Materia Medica, Chongqing Sub-center of National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Science, Chongqing Key Laboratory of Traditional Chinese Resources, Chongqing 400065, China;State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China)

机构地区：[1]重庆市中药研究院 中国中医科学院 中药资源中心 重庆分中心 中药资源学重庆市重点实验室,重庆400065 [2]中国中医科学院 中药资源中心 道地药材国家重点实验室培育基地,北京100700

出　　处：《中国中药杂志》2018年第8期1732-1736,共5页China Journal of Chinese Materia Medica

基　　金：中央本级重大增减支项目(2060302);2013年中医药部门公共卫生专项(财社[2013]135号);重庆市基本科研业务费项目(cstc2017jxjl-jbky0039);全国中药特色技术传承人才培训项目

摘　　要：百合为传统常用中药材,来源于多种药用植物,历代本草对其正品基原和质量记载有所差异,为正本清源,该文通过百合的本草学考证,结合调查研究,对其基原及品质进行系统考证。考证结果发现,古代本草记载的药用百合主要来源白花、红黄花、红花3类,各本草均记载白花类的百合Lilium brownii var.viridulum为正品或质量为好,多数本草记载红花类的山丹（细叶百合）L.pumilum或渥丹L.concolor,以及红黄花的卷丹L.lancifolium质量差不堪入药,或者单列与百合功效不同。而据2015年版《中国药典》记载,除渥丹外,其余均为百合药材来源品种,且从实际调查发现,现在药用百合的主流品种已变更为卷丹,与古文献记载有很大的差异,虽然现代化学和药理研究为卷丹的应用提供了参考依据,但仍应遵重古文献的实际记载,充分进行药效物质基础研究,为百合不同基原品种的临床应用提供科学依据。Lilii Bulbus,which comes from many medicinal plants,is a frequently-used traditional Chinese medicine,the records in previous herbal literatures of it＇s origin and quality were inconstant. To trace back it＇s sources,we conducted a systematical study on it＇s origin and quality by textual research and investigation in this paper,The result showed that the origins of Lilii Bulbus are mainly source from white-flowers,red-yellow-flowers and red-flowers of Lilium,L. brownii var. viridulum,which were believed authentic or good quality in all previous herbal literatures,and L. pumilum and L. concolor which belong to white-flowers,and L. lancifolium which belong to red-yellow-flowers were believed low-quality and unfit for medicinal uses,or they were listed below and often have different effect with L. brownii var. viridulum. Among them,only L. concolor does not belong to Lilii Bulbus according to Chinese Pharmacopeia（ 2015 edition）,The mainstream varieties of Lilii Bulbus became L. lancifolium now according to our practical investigation,which were very different from previous herbal literatures. Although chemical and pharmacological studies provided a reference for L. lancifolium,we should respect the actual records of the previous herbal literatures,the research of material foundation of efficacy should be more sufficient,and provide science evidence for clinical application of different species of Lilii Bulbus.

关 键 词：百合 本草考证 基原 品质评价 

分 类 号：R281[医药卫生—中药学]