奥司他韦治疗儿童流行性感冒疗效观察  

Oseltamivir in the Treatment of Influenza-Like Illness in Children

作　　者：詹峰[1] 钟冲[1] 金桂红[1] Zhan Feng;Zhong Chong;Jin Guihong(The First People＇ s Hospital of Chuzhou, Anhui Chuzhou 239000, Chin)

机构地区：[1]滁州市第一人民医院,安徽滁州239000

出　　处：《儿科药学杂志》2018年第6期28-30,共3页Journal of Pediatric Pharmacy

摘　　要：目的:观察奥司他韦治疗儿童流行性感冒的临床疗效。方法:选取流感样患儿124例,随机均分为治疗组64例和对照组60例,所有患儿均行血常规和C反应蛋白检查,并做咽试子病毒分离。治疗组口服奥司他韦颗粒,对照组口服小儿豉翘清热颗粒,两组疗程均为5 d,比较两组患儿治疗后疗效及不良反应发生情况。结果:治疗组总有效率为90.6%,高于对照组的76.7%,差异有统计学意义(P<0.05);治疗期间治疗组药物不良反应发生率低于对照组。结论:奥司他韦治疗流感样患儿的临床疗效满意。Objective： To observe the clinical efficacy of oseltamivir in the treatment of influenza-like illness in children. Methods： A total of 124 children with influenza-like illness were randomly divided into the treatment group （n = 64 ） and the control group （n = 60 ）. Blood routine and C-reactive protein tests were performed in all children, and all children were isolated with throat test virus. The treatment group was treated with oral osehamivir granules. The control group received Chiqiao Qingre granules. The treatment course lasted for five days. The efficacy and adverse reactions were compared between two groups. Results： The total effective rate of treatment group was 90. 6% , higher than that of control group （ 76. 7% ） , with statically significant difference （ P〈0. 05 ）. The incidence of adverse reactions in treatment group was lower than that in control group. Conclusion： The efficacy of oseltamivir in the treatment of influenza-like illness is satisfactory in children.

关 键 词：奥司他韦 流行性感冒 儿童 

分 类 号：R725[医药卫生—儿科]