Invasive mucinous adenocarcinoma with lepidic-predominant pattern coexisted with tuberculosis： a case report  

作　　者：Xinxin Xu Yinshi Guo Qiuying Li Ling Yang Jianqiang Kang 

机构地区：[1]Department of Geriatrics, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China [2]Allergy Department, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China [3]Department of lnterventional Radiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China

出　　处：《Frontiers of Medicine》2018年第3期330-333,共4页医学前沿（英文版）

基　　金：The support from National Natural Science Foundation of China （No. 81200017） and Foundation of Traditional Chinese and Western Medicine of General Hospitals in Shanghai （No. ZHYY-ZXYJHZX- 2-201701 ） is gratefully acknowledged.

摘　　要：We observed a rare case of invasive mucinous adenocarcinoma （IMA） with a lepidic-predominant pattern accompanied by pulmonary tuberculosis. An 85-year-old man with repeated cough and sputum was admitted to Xinhua Hospital. T-SPOT test result was 212 pg/ml （reference value of negative is 〈 14 pg/ml）, Mycobacterium tuberculosis culture was positive, and tuberculin skin test （PPD） was negative （skin induration 〈 5 mm）. The patient was treated with several courses of antibiotics and anti-tuberculosis treatments. Repeated chest CT scans showed disease progression. Bronchoscopy yielded negative results. PET-CT scans showed negative results. A percutaneous lung biopsy revealed mucin-secreting cells lining the alveolar walls. IMA with a lepidic- predominant pattern was diagnosed after invasiveness was found after experimental treatments. Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present case of IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported yet.We observed a rare case of invasive mucinous adenocarcinoma （IMA） with a lepidic-predominant pattern accompanied by pulmonary tuberculosis. An 85-year-old man with repeated cough and sputum was admitted to Xinhua Hospital. T-SPOT test result was 212 pg/ml （reference value of negative is 〈 14 pg/ml）, Mycobacterium tuberculosis culture was positive, and tuberculin skin test （PPD） was negative （skin induration 〈 5 mm）. The patient was treated with several courses of antibiotics and anti-tuberculosis treatments. Repeated chest CT scans showed disease progression. Bronchoscopy yielded negative results. PET-CT scans showed negative results. A percutaneous lung biopsy revealed mucin-secreting cells lining the alveolar walls. IMA with a lepidic- predominant pattern was diagnosed after invasiveness was found after experimental treatments. Simultaneous occurrence of pulmonary tuberculosis and lung cancer are common; however, the present case of IMA having a lepidic-predominant pattern and coexisting with active tuberculosis has not been reported yet.

关 键 词：[nvasive mucinous adenocarcinoma lepidic-predominant TUBERCULOSIS 

分 类 号：TS101.923[轻工技术与工程—纺织工程] X703.1[轻工技术与工程—纺织科学与工程]