美洲大蠊研究现状及其研究中关键问题分析与展望  

Research status of Periplaneta americana with analyses and prospects of key issues

作　　者：李奇娟[1] 王战国[2] 刘巧[1] 谢余 胡慧玲[1] LI Qi-juan;WANG Zhan-guo;LIU Qiao;XIE Yu;HU Hui-ling(Key Laboratory of Standardization of Chinese Herbal Medicine, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Ministry of Education, State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu 611137, China;Collaborative Innovation Laboratory of Metabonomics, College of Medicine, Chengdu University, Standard Research and Extension Base （Collaborative Innovation Center） of Qiang Medicine, Chengdu 610106, China)

机构地区：[1]成都中医药大学药学院、中药材标准化教育部重点实验室、中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都611137 [2]成都大学医学院代谢组学协同创新实验室、羌医药标准研究推广基地暨协同创新中心,四川成都610106

出　　处：《中国中药杂志》2018年第7期1507-1516,共10页China Journal of Chinese Materia Medica

基　　金：四川省科技厅项目(2016NZYZF0015);2015年博士后培养基金项目(008051)

摘　　要：美洲大蠊,是我国传统中药蜚蠊的基源药材之一,应用历史悠久,具有健脾消疳,活血通脉,利水消肿生肌等功效。临床上多用于治疗多种消化道疾病、慢性心力衰竭、皮肤及黏膜损伤、手术后伤口创面的修复、牙周炎等;常用的代表制剂有康复新液、心脉隆注射液、肝龙胶囊、消癥益肝片等。该文从化学成分、药理作用、临床应用等角度对美洲大蠊现代药用研究进行了全面总结,并首次对美洲大蠊及其相关制剂质量控制现状进行了系统梳理。针对美洲大蠊研究中的关键问题进行归纳分析,为其进一步的开发与临床应用提供参考。Periplaneta americana is one of the common traditional Chinese medicines,which has a long application history. It can tonify spleen,promote blood circulation,induce diuresis to alleviate edema,and promote granulation. It is clinically used for the treatment of alimentary canal diseases,chronic heart failure,cutaneous lesion,periodontitis and other diseases. There are some representative prescriptions,such as Kangfu Xinye,Xinmailong injection,Ganlong capsule,and Xiaozheng Yigan tablet. This paper reviewed the chemical components,pharmacological effects and clinical applications of P. americana,firstly summarized standards for the quality control of P. americana,found out and analyzed the key problems in the research. The aim of this paper is to provide the references for the further development and application of P. americana.

关 键 词：美洲大蠊 化学成分 生物活性 质量控制 研究进展 关键问题 

分 类 号：R282.74[医药卫生—中药学]