当归补血汤在血液疾病中作用机制的研究进展  

Research progress on mechanism of Danggui Buxue Decoction in hematologic disease

作　　者：谢东杰[1] 王爱迪[1] 刘宝山[1] XIE Dong-jie;WANG Ai-di;LIU Bao-shan(Tianjin Medical University General Hospital, Tianjin 300041, China)

机构地区：[1]天津医科大学总医院,天津300041

出　　处：《中华中医药杂志》2018年第6期2488-2490,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81373847)~~

摘　　要：当归补血汤作为一首补气生血之名方,现代药理研究已经对其进行了多方面的探索,包括促进骨组织修复,改善循环、保护肾组织、抗纤维化、调节免疫、促进造血等作用。但该方在血液疾病中起效的作用机制笔者尚未见系统的总结分析。文章通过查阅当归补血汤在血液疾病及与血液疾病存在相同病理机制疾病的研究文献,从当归补血汤的经典配伍、调节免疫系统,维持机体免疫耐受、促进骨髓造血系统重建、对传导通路的调节等方面对该方在血液疾病中发挥效用的作用机制作一综述,以期为该方在临床的应用提供理论基础及科学依据。Danggui Buxue Decoction is a famous Chinese medicinal prescription with the effect of benefiting qi and nourishing blood. Modern pharmacological research has been carried out in many aspects, including promoting bone repair, improving circulation, protecting kidney tissue, anti-fibrosis, regulating immunity, promoting hematopoiesis, and so on. However, the mechanism of this prescription in the blood system diseases has not been systematically analyzed. In this paper, by summarizing literatures about Danggui Buxue Decoction in blood diseases and diseases with similar mechanism as blood diseases, a review of the mechanism of Danggui Buxue Decoction in blood disease has been made from the aspects of the classical compatibility, the regulation of the immune system, the maintenance of the immune tolerance of the body, the promotion of the reconstruction of the hematopoietic system of the bone marrow, the regulation of the conduction pathway and so on, hoping to provide theoretical basis and scientific basis for its clinical application.

关 键 词：当归补血汤 血液疾病 作用机制 

分 类 号：R259[医药卫生—中西医结合]