迁徙对人群糖代谢的影响  

Effects of migration on glucose metabolism of the population

作　　者：张星星 石勇铨 Zhang Xingxing;Shi Yongquan(Department of Endocrinology, Changzheng Hospital, The Navy Military Medical University, Shanghai 200003, Chin)

机构地区：[1]海军军医大学附属长征医院内分泌科,上海200003

出　　处：《中华内分泌代谢杂志》2018年第5期442-446,共5页Chinese Journal of Endocrinology and Metabolism

摘　　要：迁徙多数发生在从欠发达地区至发达地区（大部分研究涉及从南亚地区迁徙至欧洲的人群），研究发现，与当地人相比，迁徙人群的糖尿病患病风险更高，且患病年龄提前，胰岛素抵抗更重且胰岛β细胞功能更容易发生衰竭，从而导致其大血管、微血管等糖尿病并发症明显增高。这些差异可能与迁徙人群的遗传、表观遗传、生活方式和社会保障等有关。Most migrations occur movement from less developed regions to developed areas （ most of which involve people migrating from South Asia to Europe ）. Migrants had a higher risk of diabetes in the migratory population than that in the locals, earlier of illness, more severe insulin resistance, and more likely failure of pancreatic β cell function, which lead to increased complications such as macrovasular and microvascular diseases. These differences may be related to the genetic, epigenetic, lifestyle, as well as the social security of the migrant population.

关 键 词：糖尿病 迁徙 患病率 Β细胞功能 并发症 

分 类 号：R587.1[医药卫生—内分泌]