严重发热伴血小板减少综合征病毒在输血安全中的研究进展  

Severe fever with thrombocytopenic syndrome virus( SFTSV ) in transfusion safety: A progress review

作　　者：赵航 李世林[1] 曾沛斌[1] 陈利民[1] 杨春晖[1] ZHAO Hang;LI Shilin;ZENG Peibin;CHEN Limin;YANG Chunhui.(Institue of Blood Transfuson, Chinese Academy of Medical Sci- ences and Peking Union Medical College, Provincial key Laboralary for Transfusion transmitted Diseases of Sichuan Province, Chengdu 610052, China.)

机构地区：[1]中国医学科学院北京协和医学院输血研究所四川省输血传播疾病医学重点实验室

出　　处：《中国输血杂志》2018年第3期306-310,共5页Chinese Journal of Blood Transfusion

基　　金：中国医学科学院医学与健康科技创新工程(2016-I2M-3-025)

摘　　要：严重发热伴血小板减少综合征病毒（SFTSV）,又名蜱虫病病毒,是近年来在我国部分地区传播的新发血液传播病毒,由病毒引起的严重发热伴血小板减少综合征具有较高的死亡率。献血者的病原体筛查是保障血液安全的重要手段之一。目前,我国采供血机构只筛查艾滋病病毒,乙肝病毒,丙肝病毒和梅毒螺旋体4种血液传播病原体,SFTSV等新发血液传播病原体可能威胁我国血液安全。我们将对SFTSV的病原学,检测方法和流行病学等方面进行综述,并进一步探讨SFTSV对我国血液安全的潜在威胁。Severe fever with thrombocytopenia syndrome virus（ SFTSV）,also known as the tick-borne disease virus,is a new-found blood-borne virus that had spread in some areas of our country in recent years. The severe fever with thrombocytopenia syndrome caused by such virus often resulted in high mortality during treatment. To cope with this risk,the pathogen screening of blood donors is one of the important strategies adopted to ensure blood safety. In China,only HIV,HBV,HCV and Treponema pallidum were examined in routine donor screening tests. Therefore,SFTSV and other emerging pathogens which are not included in these routine tests may threaten the blood safety condition in China. In this paper,the etiology,detection methods and epidemiology of SFTSV are reviewed,and the potential threat of SFTSV to Chinese blood safety is further explored.

关 键 词：严重发热伴血小板减少综合征病毒 感染 输血安全 

分 类 号：R331.143[医药卫生—人体生理学] R457.1[医药卫生—基础医学]