纳米雄黄的药理活性及毒性研究进展  

Research progress of pharmacological activity and toxicity of realgar nanoparticles

作　　者：李少元[1] 杨旭萍 张尊建[1] 黄寅[1,2] LI Shao-yuan;YANG Xu-ping;ZHANG Zun-jian;HUANG Yin(Key Laboratory of Drug Quality Control ＆ Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009;Department of Pharmaceutical Analysis, College of Pharmacy China Pharmaceutical University , Nanjing 210009)

机构地区：[1]中国药科大学药物质量与安全预警教育部重点实验室,南京210009 [2]中国药科大学药学院药物分析系,南京210009

出　　处：《中南药学》2018年第5期661-664,共4页Central South Pharmacy

基　　金：国家自然科学基金资助项目(No.81403181);江苏省自然科学基金资助项目(No.BK2014064)

摘　　要：纳米雄黄是由传统矿物中药雄黄制备而成的纳米级药物,具有生物利用度高、靶向性强等生物学特征。本文综述了近年来纳米雄黄在药理及毒性作用方面取得的最新研究进展,为其深入研究开发提供参考。Realgar nanoparticles are a nano-drug prepared from the traditional Chinese medicine realgar with high bioavailability, strong targeting and other biological characteristics. This paper reviewed the research progress of phan-nacological and toxic effects of realgar nanoparticles in recent years and provided references for further research and development.

关 键 词：纳米雄黄 抗肿瘤 毒性 作用机制 

分 类 号：R282[医药卫生—中药学]