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作 者:唐树彬[1] 侯陈亮 邹安娜[1] TANG Shu-bin;HOU Chen-liang;ZOU An-na(Department of Oncology, The First Peoples Hospital of Neijiang, Neijiang 641000, China)
机构地区:[1]内江市第一人民医院肿瘤科,四川内江641000
出 处:《中国医药指南》2018年第9期7-7,9,共2页Guide of China Medicine
摘 要:目的观察艾迪注射液胸腔灌注联合热疗治疗恶性胸腔积液的疗效及不良反应。方法恶性胸腔积液患者78例,随机分成2组,治疗组采取艾迪注射液胸腔内灌注联合热疗,对照组仅单纯艾迪注射液灌注治疗,4周后评价疗效、生存质量及毒性反应情况。结果治疗组有效率85.7%,对照组63.89%,两组比较差异显著(P<0.05);治疗组生存质量明显改善,未明显增加组毒性反应。结论热疗联合艾迪胸腔内注射治疗恶性胸腔积液是一种有效率高、毒性反应小、耐受性好的有效方法。Objective To investigate the efficacy and side effects with malignant pleural effusion treated by pleural cavity infusion Ai Di Combined with Hyperthermia. Methods Seventy-eight patients with malignant pleural effusion were randomly divided in to treated group and control group. For treated group, Ai Di was injected into pleural cavity followed by hyperthermia, for the control group, were treated only with pleural cavity infusion Ai Di. The efficacy of pleural effusion was investigated after four weeks. Results The overall response rate of the two groups were 85.7% and 63.89%, statistically significant difference wag found(P〈0.05). The quality of life improved evidently in treated group. Conclusion The efficacy to malignant pleural effusion of hyperthermia combined with pleural cavity infusion of Ai Di is better than those of the method of only pleural cavity infusion of Ai Di. The treatment is well tolerated with no adverse toxic reaction.
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