前列腺动脉栓塞治疗良性前列腺增生患者生活质量观察  

Observation of quality of life in patients with benign prostatic hyperplasia after prostatic artery embolization

作　　者：郭晓华[1] 朱德胜[2] 吴海啸[2] 胡晓钢[1] 徐旻[2] 吴汉[2] 孙鹏[2] GUO Xiaohua;ZHU Desheng;WU Haixiao;HU Xiaogang;XU Min;WU Han;SUN Peng(Department of Interventional Radiology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang Province 321000, China)

机构地区：[1]金华市中心医院介入科,浙江321000 [2]金华市中心医院泌尿外科,浙江321000

出　　处：《介入放射学杂志》2018年第6期578-581,共4页Journal of Interventional Radiology

基　　金：浙江省金华市科技局重点项目(2017-3-008)

摘　　要：目的 评价前列腺动脉栓塞术(PAE)治疗良性前列腺增生后患者生活质量改善情况。方法2015年5月至2017年3月采用PAE术治疗31例重度前列腺增生患者。患者年龄80~95岁,平均(85.8±4.68)岁;国际前列腺症状评分(IPSS)为25~35分,平均(33.4±2.8)分;前列腺症状生活质量(QOL)评分为5~6分,平均(5.7±0.5)分;前列腺体积(PV)为73~178 cm3,平均(123.0±34.0)cm3。根据手术前后IPSS、QOL评分、PV评估治疗效果。结果 31例患者均成功接受PAE术。手术时间51~150 min,平均(65±13)min,术中无严重并发症发生。随访1~11个月,平均(5.0±3.4)个月。术后2周IPSS、QOL评分与术前基数水平比较,差异均无统计学意义(P>0.05)。随访期间除1例症状无明显改善外,其余30例IPSS、QOL评分均显著低于基数水平(P<0.000 1),临床症状得到改善。结论 PAE术治疗重度前列腺增生可有效改善患者排尿困难症状,提高生活质量,是一种安全、有效、可行的手术方式。Objective To evaluate the improvement of the quality of life （QOL） in patients with benign prostatic hyperplasia （BPH） after receiving prostatic arterial embolization （PAE） treatment. Methods From May 2015 to March 2017, PAE was performed in 31 patients with severe BPH. The age of patients ranged from 80 to 95 years old, with a mean of （85.8±4.68） years old. Before PAE, the international prostate symptom score （IPSS） was 25-35 points, with an average of （33.4±2.8） points; the score of QOL was 5-6 points, with an average of （5.7±0.5） points; the prostatic volume （PV） was 73-178 cm^3, with a mean of （123.0±34.0） cm^3. Based on the preoperative and postoperative IPSS, QOL scores and PV values, the curative effect of PAE was evaluated. Results Successful PAE was accomplished in all 31 patients. The time spent in PAE was 51-150 minutes, with an average of （65±13） minutes; and no serious complications occmxed during PAE procedures. The patients were followed up for 1-11 months, with an average of （5±3.4） months. Two weeks after PAE, the IPSS and QOL scores showed no obvious changes when compared with the preoperative base levels, and the differences were not statistically significant （P〉0.05）. During the follow-up period, except for one patient who showed no significant improvement in clinical symptoms, in all the other 30 patients the IPSS and QOL scores were significantly lower than the preoperative base levels （P〈0.000 1 ） and the clinical symptoms were improved. Conclusion In treating patients with severe BPH, PAE can effectively improve dysuria and improve the quality of life. Therefore, PAE is a safe, effective and feasible therapeutic method.

关 键 词：良性前列腺增生 前列腺动脉栓塞术 生活质量评分 

分 类 号：R697.3[医药卫生—泌尿科学]