食管癌术后患者医院获得性肺炎病原菌及经济损失分析  

Pathogens and economic losses due to postoperative hospital-acquired pneumonia in patients with esophageal cancer

作　　者：卢珍玲[1] 秦芹 陈宝勤[1] 傅建国[1] LU Zhen-ling;QIN Qin;CHEN Bao-qin;FU Jian-guo(Zhongshan Hospital Xiamen University, Xiamen, Fujian 361004, China)

机构地区：[1]厦门大学附属中山医院院感与预防保健科,福建厦门361004

出　　处：《中华医院感染学杂志》2018年第11期1683-1685,1700,共4页Chinese Journal of Nosocomiology

基　　金：厦门市科技局基金资助项目(3502Z20174087)

摘　　要：目的分析食管癌患者术后发生医院获得性肺炎导致的直接经济损失,为及时采取医院获得性肺炎感染控制措施提供依据。方法选择2015年1月-2016年12月胸外科食管癌患者512例为研究对象,根据术后发生医院获得性肺炎情况分为感染组与对照组,各82例(1∶1配对),比较两组患者住院费用和住院时间及感染患者病原菌情况。结果 512例患者发生医院获得性肺炎82例,感染率为16.02%,感染组和对照组住院总费用分为80669.05(73957.46,92787.37)元和69800.65(64805.00,72479.03)元,感染组患者比对照组总费用多增加12886.60(5760.19,20226.63)元(P<0.001);感染组患者住院时间为35.00(28.75,42.00)天长于对照组(P<0.001)。82例患者共检出病原菌108株,其中革兰阴性菌98株占90.74%,革兰阳性菌10株占9.26%。结论食管癌患者术后医院获得性肺炎导致经济损失,应采取有效预防控制措施。OBJECTIVE To analyze the economic losses due to postoperative hospital-acquired pneumonia in patients with esophageal cancer,so as to provide references for taking immediate measures to control nosocomial infections.METHODS Five hundred and twelve patients with esophageal cancer who were hospitalized in the department of cerebral surgery from Jan.2015 to Dec.2016 were enrolled in the study.A total of 82 cases of patients with postoperative hospital-acquired pneumonia were selected as the infection group and 82 cases without infection were selected as the control group.The average expense,average hospitalization time and distribution of pathogens were observed and compared between the two groups.RESULTS Hospital-acquired pneumonia occurred in 82 cases among 512 patients,and the infection rate was 16.02%.The expenses of the infection group and the control group were 80669.05（73957.46,92787.37）yuan and 69800.65（64805.00,72479.03）yuan,and the expenses of the infection group was 12886.60（5760.19,20226.63）yuan higher than that of the control group（P〈0.001）.The hospitalization time of the infection group was 35（28.75,42.00）days,which was significantly longer than that of the control group（P〈0.001）.Totally 108 pathogens were detected from 82 patients with infections,of which 98（90.74%）strains were gram-negative bacteria,and 10（9.26%）strains were gram-positive bacteria.CONCLUSION The postoperative hospital-acquired pneumonia in patients with esophageal cancer led to economic losses,and it was necessary to take effective control measures.

关 键 词：食管癌 医院获得性肺炎 经济损失 病原菌 

分 类 号：R563.1[医药卫生—呼吸系统]