益气补肾化瘀法周期性治疗子宫内膜异位症伴不孕的临床疗效  

Clinical Effect of Endometriosis with Infertility Treated by Yiqi Bushen Huayu Cycle Therapy

作　　者：鲜恩英 李雪琴 黄莉莉[3] XIAN Enying;Li Xueqin;HUANG Lili(Department of Obstetrics and Gynecology, School of medicine, University of Tibet, Lhasa 850000, Tibet Autonomous Region;Department of Obstetrics and Gynecology, Lhasa People＇ s Hospital, Tibet, Tibet autonomous region, Lhasa 850000, Tibet Autonomous Region, China;Department of Obstetrics and Gynecology, General Hospital of Tibet military area command, Lhasa 850000, Tibet Autonomous Region, China)

机构地区：[1]西藏大学医学院妇产科教研室,西藏拉萨850000 [2]拉萨市人民医院妇产科,西藏拉萨850000 [3]西藏军区总医院妇产科,西藏拉萨850000

出　　处：《中华中医药学刊》2018年第6期1471-1474,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：西藏自治区大学生创新性实验训练计划项目(Z2012A09G09100)

摘　　要：目的：评价益气补肾化瘀法周期性治疗子宫内膜异位伴不孕的临床疗效。方法：确诊为子宫内膜异位伴不孕患者68例随机分为治疗组和对照组。治疗组采用益气补肾化瘀法周期性治疗，对照组采用右归胶囊进行治疗，3个月经周期为1个疗程，共进行2个疗程。观察两组治疗后总有效率、中医症型改善效果，比较治疗前后血清CAl25、孕激素（P）、黄体生成素（LH）和雌二醇（E2）水平，B超观察盆腔结节大小。结果：治疗组总有效率94．1％，对照组73．5％，二组具有显著性差异（P〈0．05）。与对照组比较，治疗组在改善中医证候积分，血清P、LH和E2水平，缩小盆腔结节方面效果显著优于由于对照组（P〈0．05）。二组在妊娠率和CAl25水平方面差异无统计学意义（P〉0．05）。结论：益气补肾化瘀法周期性治疗通过改善中医证候、调节患者体内生殖激素，缩小盆腔结节，以达到改善临床症状的治疗目的。Objective ： To observe the clinical effect of endomttriosis （EMS） with infertility treated with Yiqi Bushen Huayu cycle therapy. Methods：Sixty - eight patients with endometriosis and infertility were randomly divided into treat- ment group and control group. The treatment group was treated with Yiqi Bushen Huayu Recipe, while the control group was treated with Yougui Capsule. The treatment lasted for 2 courses which consisted of 3 menstrual cycles as one. The to- tal clinical effect was observed, and the improved effect of traditional Chinese medicine, levels of CA125, Progesterone （P）, luteinizing hormone （LH） and estradiol （E2 ） and pelvic nodule size were compared. Results：The total effective rate was 94.1% in the treatment group and 73.5% in the control group. There was significant difference between the two groups （P 〈 0. 05 ）. Compared with the control group, the treatment group＇ s TCM syndrome score, serum levels of P, LH and E= and narrowing pelvic nodule were significantly improved （ P 〈 0.05 ）. However, there was no significant differ- ence in pregnancy rate or CA125 level between the two groups （P 〉 O. 05 ）. Conclusions：Yiqi Bushen Huayu cycle thera- py method treating EMS with infertility can regulate the body of reproductive hormones in patients and reduce pelvic nod- ules, for the purpose of improving clinical symptoms.

关 键 词：子宫内膜异位症 不孕 周期性治疗 肾虚血瘀 

分 类 号：R711.71[医药卫生—妇产科学] R271.14[医药卫生—临床医学]