不同正压通气方式治疗早产儿呼吸窘迫综合征的临床效果分析  

Clinical effect analysis of different positive pressure ventilation in the treatment of premature infants with respiratory distress syndrome

作　　者：黄小芹 林天植 HUANG Xiao-qin;LIN Tian-zhi.(Department of Pediatrics, Shanwei People＇ s Hospital, Shanwei 516600, China)

机构地区：[1]汕尾市人民医院儿科,516600

出　　处：《中国实用医药》2018年第16期22-24,共3页China Practical Medicine

摘　　要：目的探究同步经鼻间歇正压通气(NSIPPV)和经鼻持续正压通气(NCPAP)两种不同正压通气方式在早产儿呼吸窘迫综合征(RDS)中的治疗效果。方法 83例呼吸窘迫综合征早产儿,以随机数表法分为NSIPPV组(42例)和NCPAP组(41例)。NSIPPV组早产儿行NSIPPV治疗;NCPAP组早产儿行NCPAP治疗。比较两组治疗前及治疗2、12、24 h血气指标,中转有创机械通气率。结果治疗前,两组早产儿氧分压(PaO_2)、二氧化碳分压(PaCO_2)水平比较差异无统计学意义(P>0.05);治疗2、12、24 h,NSIPPV组早产儿PaO_2水平高于NCPAP组,PaCO_2水平低于NCPAP组,差异均具有统计学意义(P<0.05)。NSIPPV组中转有创机械通气率为4.76%,低于NCPAP组的19.51%,差异具有统计学意义(χ~2=4.2598,P<0.05)。结论 NSIPPV在早产儿呼吸窘迫综合征治疗中安全有效,可快速缓解患儿的呼吸状况,值得推广。Objective To investigate the effect of two different positive pressure ventilation of nasal synchronized intermittent positive pressure ventilation（NSIPPV） and nasal continuous positive airway pressure（NSIPPV） in the treatment of premature infants with respiratory distress syndrome. Methods A total of 83 premature infants with respiratory distress syndrome（RDS） were divided by random number table method into NSIPPV group（42 cases） and NCPAP group（41 cases）. NSIPPV group was treated with NSIPPV, and NCPAP group was treated with NCPAP. The blood gas indexes before treatment and after 2, 12, and 24 h of treatment, and transfer rate of invasive mechanical ventilation between the two groups were compared. Results Before treatment, both groups had no statistically significant difference in oxygen partial pressure（PaO2） and partial pressure of carbon dioxide（PaCO2） level（P〉0.05）. After 2, 12, and 24 h of treatment, NSIPPV group had higher PaO2 than NCPAP group, and lower PaCO2 level than NCPAP group. Their difference was statistically significant（P〈0.05）. NSIPPV group had lower transfer rate of invasive mechanical ventilation as 4.76% than 19.51% in NCPAP group, and the difference was statistically significant（χ^2=4.2598, P〈0.05）. Conclusion NSIPPV synchronized intermittent positive pressure ventilation is safe and effective in the treatment of premature infants with respiratory distress syndrome, and can quickly relieve the respiratory condition of children. It is worth promoting.

关 键 词：同步经鼻间歇正压通气 经鼻持续正压通气 早产儿 呼吸窘迫综合征 

分 类 号：R722.6[医药卫生—儿科]