关节软骨缺损修复区剪切特性分析  

Analysis of shear behavior of articular cartilage defect repair area

作　　者：赵永政 刘海英 张春秋 胡亚辉 ZHAO Yong-zheng;LIU Hai-ying;ZHANG Chun-qiu;HU Ya-hui(School of Mechanical Engineering, Tianjin key Laboratory of the Design and Intelligent Control of the Advanced Meehatronieal System, 2. National Demonstration Center for Experimental Mechanical and Electrical Engineering Education （Tianjin University of Technology ）, Tianjin 300384, Chin)

机构地区：[1]天津理工大学机械工程学院天津市先进机电系统设计与智能控制重点实验室机电工程国家级实验教学示范中心(天津理工大学),天津300384

出　　处：《天津理工大学学报》2018年第3期34-41,52,共9页Journal of Tianjin University of Technology

基　　金：国家自然科学基金青年基金(11402172);国家自然科学基金重点资助项目(11432016);天津市自然科学重点基金(15JCZJC32800)

摘　　要：应用有限元软件ABAQUS建立基于横观各向同性的关节软骨固液耦合双相模型,在压缩载荷作用下,研究了工程化软骨(Tissue Engineering Cartilage,TEC)的弹性模量和泊松比、修复深度、及压缩量对修复区剪应力分布的影响.模拟结果表明,缺损修复显著地改变了修复区剪应力的分布.比较而言,全层缺损修复时软骨表层修复边界处的宿主软骨和TEC剪应力差别最小,软骨不易开裂;修复区剪应力极值随TEC弹性模量增大而增大;加载初期(2 s),剪应力极值随TEC泊松比增大而减小,加载一段时间后(1 000 s),剪应力极值随泊松比增大而增大;压缩量不同时,各种修复条件下剪应力极值均随压缩量增加而增大,且压缩量增大时,软骨表层修复边界处剪应力集中现象愈加显著,易引起开裂.分析结果对临床修复具有一定的理论指导意义.A solid-liquid coupling two-phase model of articular cartilage based on transversely isotropic was established by using finite element software ABAQUS. The purpose of the study was to investigate the shear stress distribution in repair area under compression load, the parameters as repair depths , compression, and the elastic modulus and Poisson＇s ratios of tissue engineering cartilage （TEC）took different values respectively. The simulation results showed that the defect repair significantly changed the distribution of shear stress in the repair area. Comparatively speaking, for the full-thickness defect repair, the difference of shear stress between host cartilage and TEC at the adhesion interface was the smallest, and cartilage was not easy to crack. The maximum shear stress in repair area increased with the increase of elastic modulus of TEC. At the beginning of loading （2 s）, the extreme value of shear stress decreased with the increase of Poisson^s ratio for TEC. However, after loading for a period of time （ 1 000 s ）, the extreme value of shear stress increased with the increase of Poisson＇s ratio. The maximum shear stress increases with the increase of compression for various repair situations,the shear stress concentration at the repair boundary of the cartilage surface became more and more obvious with compression increased, and which was easy to cause cracking. The results of the analysis will provide some theoretical significance for clinical repair.

关 键 词：横观各向同性 缺损修复 剪应力 有限元 

分 类 号：R318.01[医药卫生—生物医学工程]