艾滋病合并新型隐球菌性脑膜炎患者的综合治疗  

Comprehensive treatment of Cryptococcus neoformans meningitis in acquired immunodeficiency syndrome patients

作　　者：鲁雁秋 邱丹 陈耀凯[1] Lu Yanqiu;Qiu Dan;Chen Yaokai(Department of lnfectious Diseases , Department of Emergency , Chongqing Public Health Medical Center, Chongqing 400036, Chin)

机构地区：[1]重庆市公共卫生医疗救治中心感染科,400036 [2]重庆市公共卫生医疗救治中心急诊科,400036

出　　处：《中华临床感染病杂志》2018年第2期156-160,共5页Chinese Journal of Clinical Infectious Diseases

基　　金：“十三五”国家科技重大专项课题（2018ZX10302104）;北京市科技计划资助（D161100000416003）

摘　　要：新型隐球菌性脑膜炎（CNM）是艾滋病患者中最常见的机会性感染和死亡原因之一.综合治疗是降低病死率的关键,主要包括抗真菌治疗、抗反转录病毒治疗和颅内压管理.近年来,相关研究在上述各治疗环节上均取得了一定进展,本文将从这个三方面进行系统综述.Cryptococcus neoformans meningitis is one of the most common opportunistic infections and causes of death in acquired immunodeficiency syndrome（AIDS）patients with HIV infection. Comprehensive treatment is the key to reduce the mortality rate of AIDS patients with Cryptococcus neoformans meningitis,which includes antifungal treatment, antiretroviral therapy and intracranial pressure management.This article reviews the current status and advanced of comprehensive therapy for Cryptococcus neoformans meningitis in AIDS patients.

关 键 词：获得性免疫缺陷综合征 隐球菌 新型 脑膜炎 综合疗法 

分 类 号：R515.2[医药卫生—内科学]