补气健脾法改善自身免疫性甲状腺炎免疫失衡状态的研究进展  

Research progress of spleen-strengthening and Qi-invigorating herbal medicine in treatment of immune imbalance of autoimmune thyroiditis

作　　者：金哲 杨潇 梅兰 江红[1] Jin Zhe, Yang Xiao, Mei Lan, Jiang Hong(Department of Endocrinology, the Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Liaoning Institute of Traditional Chinese Medicine, Shenyang 110034, Chin)

机构地区：[1]辽宁省中医药研究院辽宁中医药大学附属第二医院内分泌科,沈阳110034

出　　处：《中国医药》2018年第7期1114-1117,共4页China Medicine

基　　金：国家自然科学基金(81503474);辽宁省科学技术计划(201501110);辽宁省教育厅科学研究一般项目(L2015347);辽宁中医药大学大学生创新创业训练计划立项项目(201510162000011)~~

摘　　要：自身免疫性甲状腺炎的发病与情志、饮食、水土、体质等因素密切相关,病及肝、脾、肾三脏,病机总属本虚标实。本文依据中医整体观念和辨证论治的理论精髓,从后天之本"脾"入手,以"补气健脾"为基本原则,以补中益气汤的前期研究成果为基础,综合机体免疫功能、神经-内分泌-免疫系统探讨补气健脾法改善自身免疫性甲状腺炎免疫失衡状态的机制。Autoimmune thyroiditis is associated with the dysfunction of liver, spleen and kidney; cause of the disease includes mutiple factors such as emotion, diet, region and body constitution. Traditional Chinese medical theory reveals the essence of treatment for autoimmune thyroiditis according to the syndrome differentiation theory; spleen-strengthening and Qi-invigorating is the basic principle of treatment. Buzhong Yiqi decoction is a classical herbal prescription that has regulatory effect on immunologic function and neuroendocrine-immune system. This paper discussed possible mechanisms of spleen-strengthening and Qi-invigorating herbal medicine in treatment of immune imbalance of autoimmune thyroiditis.

关 键 词：自身免疫性甲状腺炎 免疫功能 神经-内分泌-免疫系统 

分 类 号：R581.4[医药卫生—内分泌]