不同年龄比格犬红细胞压积、生理脆性的测定  

Study on Hematocrit and Red Cell Osmotic Fragility of Beagle Dog in Different Age

作　　者：杜志国 张廷荣[2] 宋俊霖 黄凯 王森 张丽萍[1] 温奇凤 项露娟 郭颖[5] 尹燕博[1] DU Zhi-guo;ZHANG Ting-rong;SONG Jun-lin;HUANG Kai;WANG Sen;ZHANG Li-ping;WEN Qi-feng;XIANG Lu-juan;GUO Yings;YIN Yan-bo(College of Veterinary Medicine, Qingdao Agricuhural University, Qingdao 266019, China;College of Animal Science and technology, Qingdao Agricultural University, Qingdao 266019, China;Central Laboratory, Qingdao Agricultural University, Qingdao 266200, China;Qingdao Bolong Experimental Animal Co. , Ltd. Qingdao 266200, China;Department of Blood Transfusion, General Hospital of Shenyang Military Region, Shenyang 110016, China)

机构地区：[1]青岛农业大学动物医学院,山东青岛266109 [2]青岛农业大学动物科技学院,山东青岛266109 [3]青岛农业大学中心实验室,山东青岛266200 [4]青岛博隆实验动物有限公司,山东青岛266200 [5]沈阳军区总医院输血科,辽宁沈阳110000

出　　处：《中国兽医杂志》2018年第3期76-79,I0008,共5页Chinese Journal of Veterinary Medicine

基　　金：国家重点研发计划(2017YFD0501602)

摘　　要：为了测定不同年龄比格犬红细胞压积、脆性,给动物实验提供基础数据。选取不同年龄的健康比格犬,检测其红细胞压积、脆性,并对结果进行统计分析。结果显示,红细胞压积与年龄、性别相关,成年犬红细胞压积大于幼年犬、育成犬与老年犬,差异显著;成年公犬的红细胞压积大于成年母犬,差异显著;红细胞压积随年龄增长表现为先增高后降低。红细胞脆性与年龄无直接联系,幼年公犬和成年公犬红细胞脆性的最小抵抗值差异显著,其余各生长阶段的最小抵抗值无明显差异,最大抵抗值变化较大。本次测定表明,不同性别和年龄的比格犬红细胞压积、脆性存在差异。The study was to investigate the hematocrit,red cell osmotic fragility of Beagle dog at different ages,and provide basic data for animal experiments. Healthy beagle dogs with different ages were selected,and the hematocrit and red cell osmotic fragility in dogs were studied. The results showed that the hematocrit was associated with the age and sex of dogs. The hematocrit of adult dogs was significantly higher than that in puppies,growing dogsand older dogs,respectively,and male dogs was significantly higher than that in bitches. Furthermore,the hematocrit was first increased and then decreased with the increase of ages of dogs. The red cell osmotic fragility did not have the directly relationship to the ages. Red cell osmotic fragility minimum resistance had no significant difference for every growing stage exceptmalepuppies and adult male dogs. There was significantly difference in the maximum resistance for concentration gradient of brine of red cell osmotic fragility for every growing stage and sex. This study suggests that there difference in the hematocrit and red cell osmotic fragility in Beagle dogs with differentgenders and ages.

关 键 词：比格犬 红细胞压积 红细胞脆性 

分 类 号：S858.292[农业科学—临床兽医学]