补骨脂主要不良反应的研究与思考  

Overview and Thoughts on on the Main Side Effects of Fructus Psoraleae

作　　者：穆国华[1] 石玥[1] 申萌萌[1] 吴丽婷[1] 赵青竹 刘雁峰[1] Mu Guohua;Shi Yue;Shen Mengmeng;Wu Liting;Zhao Qingzhu;Liu Yanfeng(Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China)

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《世界中医药》2018年第4期1038-1042,共5页World Chinese Medicine

基　　金：国家自然科学基金项目(81273789;81473721);2014年北京中医药大学薪火传承项目

摘　　要：本文对补骨脂的历史沿革及其主要成分做了回顾;对现代研究中补骨脂的肝、肾以及其生殖毒性进行了综述,并将其和其他中药配伍后毒性的改变进行了总结;最后由对补骨脂的认识引发对中草药及其复方用药的安全思索,以期中医药能够更加规范化、安全化的应用。In this paper,the history of Fructus Psoraleae and its main components were reviewed. The liver,kidney and reproductive toxicity of Fructus Psoraleae in modern research were reviewed and the changes of toxicity after compatibility with other Chinese medicines were summarized. Finally,the understanding of Fructus Psoraleae raised the thoughts on safety of Chinese herbal medicine and its compound medication,looking forward that the Chinese medicine can be more standardized in safe application.

关 键 词：补骨脂 主要成分 肝毒性 肾毒性 生殖毒性 综述 中草药 中药复方 

分 类 号：R284[医药卫生—中药学]