南京市成人中心性肥胖与心血管疾病危险因素聚集及患病的关系  

Relationship between central obesity and risk factors clustering or prevalence of cardiovascular diseases in adult residents of Nanjing city

作　　者：戚圣香[1] 洪忻[1] 王志勇[1] 秦真真[1] 叶青[1] 李潮[1] 马国亮[1] 徐斐[1] QI Sheng-xiang;HONG Xin;WANG Zhi-yong;QIN Zhen-zhen;YE Qing;LI Chao;MA Guo-liang;XU fei(Department of Chronic and Non-communicable Disease Control and Prevention, Nanjing Municipal Center for Disease Control and Prevention, Nanjing,Jiangsu Province 210003, China)

机构地区：[1]南京市疾病预防控制中心慢病防制科,江苏省南京210003

出　　处：《中国慢性病预防与控制》2018年第5期346-350,共5页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：2015年南京市卫计委科技发展项目(YKK15179)

摘　　要：目的分析中心性肥胖与心血管疾病危险因素(cardiovascular risk factors,CRFs)聚集及心血管疾病(cardiovascular diseases,CVDs)患病的关系,为CVDs的防控提供参考建议。方法本研究利用2011年南京市慢性病危险因素监测数据进行分析,于2011年6-11月采用多阶段整群随机抽样法,抽取南京市18岁及以上常住居民进行问卷调查、体格检查和实验室检测,共40 896人纳入分析。用2010年南京市18岁及以上常住人口普查数据,采用事后分层权重的方法对年龄、性别因素进行加权调整。采用SPSS 20.0统计软件进行χ~2检验。采用单因素和多因素logistic回归分析中心性肥胖对CRFs患病、聚集及CVDs自报患病风险的影响。结果南京市成人中心性肥胖率为42.7%,男性、≥60岁、郊区、丧偶或离异或分居、小学及以下文化程度和体力劳动者的中心性肥胖率较高,差异均有统计学意义(P<0.01)。高血压、糖尿病、血脂异常、CRFs聚集、自报冠心病和自报脑卒中的患病率分别为25.0%、6.7%、29.6%、14.3%、1.1%和1.4%,且在中心性肥胖组中的患病率高于非中心性肥胖组,差异均有统计学意义(P<0.01)。多因素logistic回归分析显示,中心性肥胖组罹患高血压、糖尿病、血脂异常、CRFs聚集、自报冠心病和自报脑卒中的风险是非中心性肥胖组的1.418、1.367、1.327、1.560、1.493和1.335倍,均有统计学意义(P<0.01)。中心性肥胖对高血压、糖尿病、血脂异常、CRFs聚集、自报冠心病和自报脑卒中的人群归因危险度百分比分别为15.1%、13.5%、12.3%、19.3%、17.4%和12.5%。结论南京市成人CRFs患病、聚集和CVDs患病的疾病负担较重,在中心性肥胖人群中患病率更高,控制中心性肥胖可以有效降低CVDs负担。Objective To analyze the relationship between central obesity and clustering of major cardiovascular risk factors（CRFs） or prevalence of cardiovascular diseases（CVDs）, and to provide the reference for prevention and control of cardiovascular diseases. Methods The data from the chronic disease risk factor surveillance of Nanjing in 2011 were analyzed in present study.From June to November of 2011, the multi-stage cluster random sampling was used to select the 40 869 residents（≥18 years old）from Nanjing city as the subjects. The investigation was performed by questionnaire, physical examination and blood test. The census data of Nanjing in 2010 were analyzed. The post-stratification weight method was used to adjust the data for age and gender. The χ2 test was used to analyze the data, and the used software was SPSS 20.0. Univariate analysis and multivariate logistic regression methods were used to analyze the influence of central obesity on clustering of major CRFs and prevalence of CVDs.Results The rate of central obesity among adults in Nanjing city was 42.7%. The morbidities of central obesity in the subjects with male, ≥60 years old, suburban, widow（divorce or separation）, low education level（≤ primary school） and in manual workers were higher（P〈0.01）. The morbidities of hypertension, diabetes, dyslipidemia, clustering of major CRFs, self-reported CHD and self-reported stroke were 25.0%, 6.7%, 29.6%, 14.3%, 1.1% and 1.4%, respectively. The morbidities of central obesity in adults were significantly higher than that of non central obesity in adults（P〈0.01）. Multivariate logistic regression analysis showed that as compared with subjects without central obesity, the risk of hypertension, diabetes, dyslipidemia, clustering of major CRFs, selfreported CHD, self-reported stroke in adults with central obesity increased（OR values were 1.418, 1.367, 1.327, 1.560, 1.493 and1.335, respectively, P〈0.01）. Population attributable risk percent（PARP） of central obesity on hypert

关 键 词：中心性肥胖 心血管疾病 聚集 

分 类 号：R54[医药卫生—心血管疾病]