桂龙咳喘宁联合头孢噻肟治疗老年人慢性支气管炎急性发作的疗效观察  

Effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis

作　　者：王娅红 Wang Yahong(Integrated Department, the Third People＇s Hospital of Xiangshan County, Zhefiang 315700, China)

机构地区：[1]浙江省象山县第三人民医院综合科,315700

出　　处：《中国基层医药》2018年第12期1510-1513,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省科技计划项目（2013C33227）

摘　　要：目的探讨桂龙咳喘宁联合头孢噻肟治疗老年人慢性支气管炎急性发作的临床效果。方法选择象山县第三人民医院2016年4月至2017年3月诊治的老年慢性支气管炎急性发作患者68例为研究对象，采用随机数字表法分为对照组34例、观察组34例。两组均进行基础对症治疗，对照组采用头孢噻肟治疗，观察组采用桂龙咳喘宁联合头孢噻肟治疗。观察两组临床效果、症状好转时间、住院时间及肺功能。结果观察组总有效率为94.12%，显著高于对照组的76.47%（χ2＝4.22，P〈0.05）。观察组咳痰、咳嗽、喘息好转时间、住院时间分别为（3.09±0.76）d、（4.28±0.83）d、（4.30±0.92）d、（7.02±0.66）d，均短于对照组的（5.93±0.60）d、（8.34±0.56）d、（9.19±1.05）d、（10.54±1.03）d（t＝17.10、23.64、20.42、16.78，均P〈0.05）；治疗后，观察组用力肺活量、一秒钟用力呼气量与用力肺活量之比分别为（3 937.48±18.99）mL、（64.28±3.45）%，均优于对照组的（3 038.42±20.31）mL、（57.88±2.89）%（t＝188.54、8.29，均P〈0.05）。结论桂龙咳喘宁联合头孢噻肟治疗老年人慢性支气管炎急性发作效果确切，可有效控制病情。ObjectiveTo investigate the clinical effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis.Methods68 patients with acute exacerbation of chronic bronchitis were selected from April 2016 to March 2017 in the Third People＇s Hospital of Xiangshan County, and they were randomly divided into control group and observation groupaccording to the digital table, with 34 cases in each group.The two groups were given symptomatic treatment, the control group received cefotaxime treatment, while the observation group was given cefotaxime combined with Guilongkechuanning.The clinical effect, symptoms improve time, hospitalization time and lung function were observed in the two groups.ResultsThe total effective rate of the observation group was 94.12%, which was significantly higher than 76.47% of the control group （χ2=4.22, P〈0.05）. The recovery time of sputum, cough, wheezing and, hospitalization time in the observation group were （3.09±0.76）d, （4.28±0.83）d, （4.30±0.92）d, （7.02±0.66）d, respectively, which were significantly shorter than those in the control group [（5.93±0.60）d, （8.34±0.56）d, （9.19±1.05）d, （10.54±1.03）d]（t=17.10, 23.64, 20.42, 16.78, all P〈0.05）. After treatment, the forced vital capacity, forced expiratory volume in one second and forced vital capacity ratio in the observation group were （3 937.48±18.99）mL, （64.28±3.45）%, respectively, which were better than those in the control group[（3 038.42±20.31）mL, （57.88±2.89）%]（t=188.54, 8.29, all P〈0.05）.ConclusionGuilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis has definite effect, which can effectively control the disease.

关 键 词：支气管炎 慢性病 桂龙咳喘宁 头孢噻肟 老年人 呼吸功能试验 疗效比较研究 

分 类 号：R562.21[医药卫生—呼吸系统]