基于品质特征的贝母类药材品种分类研究  

Study on classification Fritillaria based on quality characteristic

作　　者：张翔[1] 李文涛[1] 段宝忠[1] 黄林芳[1] ZHANG Xiang;LI Wen-tao;DUAN Bao-zhong;HUANG Lin-fang(Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences ＆ Peking Union Medical College, Beijing 100193, China)

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193

出　　处：《中草药》2018年第9期2140-2146,共7页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金面上项目:地理格局及生态驱动揭示肉苁蓉品质生态型机理(81473315);中国医学科学院医学与健康科技创新工程经费资助(2016-I2M-3-015)

摘　　要：目的建立基于品质特征的贝母类药材品种分类。方法采用本草学、生态学、中药学、植物化学、中药鉴定学,以及结合生物计量学等方法开拓性地对中药贝母地理生态分布、性状及化学成分等品质特征进行研究,并对《中国药典》2015年版贝母药材进行分类。结果结果表明贝母类药材可分为"浙贝""川贝"2个系列,建议川贝母、平贝母、伊贝母归为川贝系,浙贝母、湖北贝母归为浙贝系。结论对于《中国药典》2015年版同类多基原品种中药的"分"与"合"及贝母资源的合理开发和利用提供依据。Objectives To avoid the confusion from Fritillaria spp. in the clinical practice, quality evaluation, production, and circulation filed so as to establish Fritillaria classification based on quality characteristic. Methods The re-classifcation investigation was conducted by evaluation of ＂Beimu＂ geographical, ecological distribution, traits and chemical composition＇s characteristics of the major Fritillaria included in 2015 Edition China Pharmacopoeia. Results The results showed that Fritillaria herbs can be divided into ＂Chuanbei＂ and ＂Zhebei＂ two types, and it was recommended that F. cirrhosae, F. ussuriensis and F. pallidiflorae can be classified as ＂Chuanbei＂, whiles F. thunbergii, F. hupehensis can be classified as ＂Zhebei＂. Conclusion This paper provides an important scientific demonstration other multi-original and multi-varieties herbal medicines.

关 键 词：多基源品种 贝母分类 品质 地理分布 生态因子 性状特征 贝母辛 西贝素 贝母乙素 贝母甲素 尿苷 鸟苷 腺苷 

分 类 号：R286.6[医药卫生—中药学]