GE 3.0TMR扩散张量成像在急慢性颈髓损伤中的应用研究  

Application of GE 3.0T MR Diffusion Tensor Imaging in Acute and Chronic Cervical Spinal Cord Injury

作　　者：万志方[1] 孟志华[1] 潘高升[1] 陈振松[1] 卢贤忠 罗煜岐 黄钟情 Wan Zhifang(Department of Imaging Diagnosis ,Yuebei People＇s Hospital, Shaoguan 512026)

机构地区：[1]粤北人民医院影像诊断科,韶关512026

出　　处：《数理医药学杂志》2018年第6期895-898,共4页Journal of Mathematical Medicine

基　　金：韶关市科技局计划项目;编号WSTJJ20120925

摘　　要：目的:运用GE 3.0T MR探讨扩散张量成像在急、慢性颈髓损伤早期诊断中的应用价值。方法:选择某院34例健康检查者(包括10例健康志愿者和24例颈椎检查阴性患者)作为对照组(A组),36例颈椎病患者和15例急性颈部外伤者(D组)行颈椎MR及DTI扫描,依据颈椎间盘突出程度和有无T2WI高信号将颈椎病患者分为B、C组。结果:A组正常成人颈髓平均FA值为(0.639±0.026),ADC值为(1.127±0.017)×10-3 mm2/s;比较A、B、C 3组,FA值逐渐下降,ADC值逐渐升高,组间比较有统计学意义(P<0.05);D组与A组比较,FA值明显下降,ADC值轻度减低,前者有统计学意义(P<0.05)。结论:颈髓DTI成像能早期诊断颈髓急、慢性损伤,通过各参数值变化预测颈髓损伤程度,为临床提供更多信息。Objective：To evaluate the application value GE 3.0 T MR diffusion tensor imaging in the early diagnosis of acute and chronic cervical spinal cord injury.Methods：34 healthy examiners in a hospital（including 10 healthy volunteers and 24 patients with negative cervical spine examination）were selected as control group（group A）,and 36 patients with cervical spondylosis and 15 patients with acute cervical trauma were examined by Mr and DTI.According to the degree of cervical disc herniation and the presence of T2 WI high signal,patients with cervical spondylosis were divided into group B and C.Results：The average FA value of cervical spinal cord in normal adults in group A was（0.639±0.026）,and the ADC value was（1.127±0.017）×10-3 mm2/s.The FA value decreased gradually and the ADC value increased gradually in the three groups,and there was significant difference among the three groups（P〈0.05）.Compared with group A,the FA value decreased significantly and ADC value slightly decreased in group D,and the difference of the former was statistically significant（P〈0.05）.Conclusion：Cervical spinal cord DTI imaging can early diagnose acute and chronic injury of cervical spinal cord.The degree of cervical spinal cord injury can be predicted by the change of parameters,which provides more information for the clinic.

关 键 词：扩散张量成像 磁共振成像 颈髓损伤 各向异性值 表观扩散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学]