戈舍瑞林联合腹腔镜治疗卵巢型子宫内膜异位症的临床观察  

Observation of Goserelin Combined With Laparoscopic Treatment of Ovarian Endometriosis

作　　者：朱娟 ZHU Juan(Department of Obstetrics and Gynecology, Ezhou Maternal and Child Health-Care Hospital, Ezhou Hubei 436000, Chin)

机构地区：[1]鄂州市妇幼保健院妇产科,湖北鄂州436000

出　　处：《中国继续医学教育》2018年第17期131-133,共3页China Continuing Medical Education

摘　　要：目的探讨戈舍瑞林联合腹腔镜治疗卵巢型子宫内膜异位症的临床效果。方法选取68例分为两组,对照组实施腹腔镜手术治疗,观察组在对照组的基础上应用戈舍瑞林进行注射治疗,观察两组患者临床效果。结果观察组患者、对照组患者临床治疗总有效率、2年内妊娠率分别为97.1%、61.8%和76.5%、20.6%,差异有统计学意义(χ~2=5.39,4.87,P<0.05)。两组患者治疗后血清激素水平显著低于治疗前(t=4.39、5.87、6.59;8.30、7.47、5.14,P<0.05)。观察组患者、对照组患者不良反应发生率分别为2.9%、26.5%,差异有统计学意义(χ~2=6.39,P<0.05)。结论采用戈舍瑞林联合腹腔镜治疗可以显著提高治疗效果。Objective To investigate the clinical effect of goserelin combined with laparoscopic treatment of ovarian endometriosis. Methods 68 cases were divided into two groups, the control group received laparoscopic operation treatment, the observation group based on the injection application goserelin, the clinical curative effect of two groups wascompared. Results The total effective rate and the 2 year pregnancy rate in the observation group and the control group were 97.1%, 61.8%, 76.5% and 20.6%, respectively, there were significant difference between two groups（χ^2=5.39,4.87, P﹤0.05）. The level of serum hormone after treatment in the two groups was significantly lower than that before treatment, there were significant difference（t=4.39, 5.87, 6.59, 8.30, 7.47, 5.14, P﹤0.05）. The incidence of adverse reactions of the patients in the observation group and the control group was 2.9% and 26.5%, there were significant difference between two groups（χ^2=6.39, P﹤0.05）. Conclusion Using goserelin combined laparoscopic treatment can significantly improve the therapeutic effect.

关 键 词：戈舍瑞林 腹腔镜 卵巢型 子宫内膜异位症 激素水平 不良反应 

分 类 号：R711.71[医药卫生—妇产科学]