前列地尔联合小剂量多巴胺对老年冠心病造影剂肾病的保护研究  

Effect of alprostadil combined with dopamine in preventing contrast induced nephropathy in elderly people underwent percutaneous coronary intervention(PCI)

作　　者：袁彬[1] 冯凯[1] 沈巍[1] 邱炜炜[1] 季小波[1] 蒋敏勇[1] 黄辉[1] 高永兴[1] 祝兴超[1] 薛勇[1] YUAN Bin;FENG Kai;QIU Wei-wei;JI Xiao-bo;JIANG Min-yong;HUANG Hui;GAO Yong-xing;ZHU Xing-chao;XUE Yong(Department of Cardiology, Jiangyin Hospital of traditional Chinese Medicine,Jiangsu Jiangyin 214400,China)

机构地区：[1]江阴市中医院心内科,江苏江阴214400

出　　处：《中西医结合心血管病电子杂志》2018年第11期66-67,共2页Cardiovascular Disease Electronic Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的探讨前列地尔联合小剂量多巴胺对老年冠心病造影剂肾病的影响。方法 86例老年冠心病行PCI患者分为两组,治疗组给予前列地尔联合多巴胺治疗,观察术后肌酐水平、肌酐清除率及造影剂肾病发生率。结果治疗组术后肌酐水平、肌酐清除率较对照组明显改善,造影剂肾病发生率明显下降。结论前列地尔联合小剂量多巴胺能降低PCI术后造影剂肾病(CIN)发生率。Objective To investigate protection effect of alprostadil combined with dopamine in elderly patients underwent percutaneous coronary intervention（PCI）.Methods 86 elderly patients were divided into two groups,treatment group were given alprostadil with dopamine,creatinine,creatinine levels,creatinine clearance rate,incidence of contrast induced nephropathy（CIN） were observed after PCI.Results Creatinine levels、creatinine clearance rate rate were improved in treatment group,the incidence of contrast induced nephropathy（CIN） were decreased.Conclusion Alprostadil combined with dopamine could reduce the incidence of contrast induced nephropathy（CIN）

关 键 词：前列地尔 多巴胺 造影剂肾病 保护作用 

分 类 号：R692.5[医药卫生—泌尿科学]