双波长比值光谱差异度指数用于人体舌苔舌质分离  

Separation of Tongue Coat and Tongue Proper Based on Optical Spectrum Dissimilarity Index Using Double-Wavelength Ratio

作　　者：刘明[1] 赵静[2] 吴太夏 张立福 汤宏颖[4] 陆小左[2] 李刚[5] LIU Ming;ZHAO Jing;WU Tai-xia;ZHANG Li-fu;TANG Hong-ying;LU Xiao-zuo;LI Gang(Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China;Institute of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China4. Institute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, Beijing 100101, China5. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650504, China)

机构地区：[1]中国医学科学院北京协和医学院生物医学工程研究所,天津300192 [2]天津中医药大学中医药工程学院,天津300193 [3]中国科学院遥感与数字地球研究所,北京100101 [4]昆明理工大学信息工程与自动化学院,云南昆明650504 [5]天津大学精密测试技术及仪器国家重点实验室,天津300072

出　　处：《光谱学与光谱分析》2018年第6期1798-1803,共6页Spectroscopy and Spectral Analysis

基　　金：协和青年科研基金项目(3332016103); 国家自然科学基金项目(81202643,81774148); 云南省教育厅科学研究基金项目(2015Z045)资助

摘　　要：舌苔舌质信息定量描述作为中医舌诊的重要内容,直接影响到中医临床舌诊的准确性。基于生物医学光子学理论,利用高光谱技术,提出一种基于双波长比值光谱差异度指数进行人体舌质舌苔分离的光谱分析新方法。首先采集被测对象371.200~992.956nm之间共343个波长的舌体高光谱信息,随机选取15位被测对象进行光谱特征分析。绘制15位被测对象舌质舌苔全波段光谱曲线并进行比较,通过观察发现,舌质舌苔反射光特征差异与血红蛋白在该波段的光学特征变化相吻合,在500~750nm之间,水对光的吸收很少,而舌体表面布满血管,光的吸收主要受到血红蛋白的影响,基于舌质舌苔在573和700nm两波段光谱吸收差异,计算双波长比值,提取舌质舌苔光谱特征差异度指数,根据个体差异,分别提取不同被测对象舌质舌苔光谱特征差异指标,进行舌质舌苔区域分离,实验结果发现,对同一被测对象舌体苔质提取光谱差异度指数SDI,舌苔舌质光谱差异度指数存在一定差异性,由于个体的不同,具有各自明显的舌质、舌体差异度指数分割线,实验结果表明,运用双波长比值光谱差异度指数的光学表达形式能够用于舌质舌苔分离,同时该方法也能够为进一步中医临床舌诊提供客观依据。Quantitative description of the tongue proper and tongue coat isperceivedas the important content for tongue diagnosis in traditional Chinese medicine,which directly affects the accuracy of clinical diagnosis.A new method fortongue proper and tongue coat separationusing spectrum dissimilarity index（SDI）by double-wavelength ratio is presented,which isbased on hyper spectroscopy and theory of biomedical photonics.The 343 wavelengths of hyperspectral tongue information of subjects is obtained in the range of 371.200 to 992.956 nm.Moreover,the hyperspectral data of 15 subjects is selected randomly for spectral characteristics analysis.By comparison with the spectral curve of the wavelength range,it can be seen that optical spectrum characteristic dissimilarity between tongue proper and tongue coat is resemble the optical characteristic of hemoglobin,since the surface of the tongue is full of blood vessels and the absorption of water is small in the range of 500 to 750 nm.In addition,double wavelength optic reflection ratio is used to extract optical spectrum characteristic dissimilarity index of tongue proper and tongue coat based on spectral absorption features of hemoglobin atthe wavelength of 573 and 700 nm,finally tongue proper and tongue coat is separated.It is can be seen that the SDI with tongue proper and tongue coat of one subject is a certain difference and has the obvious difference index line between tongue proper and tongue coat.The experiment results show that spectrum dissimilarity indexis very helpful for tongue coat and tongue proper separation in traditional Chinese medicine,and this new analysis approach may providean objective standard for TCM tongue diagnosis.

关 键 词：双波长比值 光谱差异度指数 舌苔 舌质 分离 

分 类 号：O433.4[机械工程—光学工程]