我院住院患者地塞米松磷酸钠注射液使用专项点评及分析  

Special Comment on the Use of Dexamethasone Sodium Phosphate Injection of Inpatients in Our Hospital

作　　者：赵黎明 徐晓娣 李阳 袁颐捷 凌琳 刘炎 程娟 吴华 ZHAO Liming;XU Xiaodi;LI Yang;Yuan Yijie;LING Lin;LIU Yan;CHENG Juan;WU Hua(Dept. ofPharmacy,Hefei Binhu Hospital,Hefei 230601,China)

机构地区：[1]合肥市滨湖医院药学部,合肥230601

出　　处：《中国药房》2018年第10期1421-1425,共5页China Pharmacy

基　　金：合肥市自主创新政策"借转补"项目(No.合政[2014]62号)

摘　　要：目的:为促进地塞米松磷酸钠注射液的临床合理使用提供参考。方法:制定专项点评标准及评价细则,回顾性抽取我院2014年7月-2015年6月共1 273例次使用地塞米松磷酸钠注射液的住院患者病历,进行用药合理性评价和分析。结果:地塞米松磷酸钠注射液的使用数量和例次以血液/肿瘤内科、产科、急诊微创外科、胃肠外科、急诊创伤骨科和甲状腺乳腺外科较多,以新生儿科、感染科和康复科较少。点评发现地塞米松磷酸钠注射液使用不合理病例共138例次,总体不合理使用率为10.84%;不合理使用类型包括适应证不适宜(或存在禁忌证)(59.42%)、联合用药不适宜(18.84%)、遴选药物不适宜(15.94%)、用法用量不适宜(3.62%)、药品剂型或给药途径不适宜(2.17%)等。通过开展专项点评,地塞米松磷酸钠注射液不合理使用率逐月稳步下降,由2014年7月的30.35%降至2015年6月的7.81%;同时,就该药临床使用形成了5点院内共识。结论:我院地塞米松磷酸钠注射液在临床使用中存在不合理现象,尤以适应证方面的不合理现象较为突出;专项点评工作的开展有效提高了该药使用的合理性,今后仍应持续进行并不断完善。OBJECTIVE：To provide reference for promoting the rational use of Dexamethasone sodium phosphate injection in the clinic. METHODS：Special comment criteria and evaluation rules was formulated,medical records of 1 273 inpatients receiving Dexamethasone sodium phosphate injection were collected from our hospital during Jul. 2014-Jun. 2015. Rationality of drug use was evaluated and analyzed retrospectively. RESULTS： The most use amount and case number of Dexamethasone sodium phosphate injection were in the departments of blood/oncology,obstetrics,emergency minimally invasive surgery,gastrointestinal surgery,emergency trauma of orthopedics and thyroid breast surgery;while much less were in departments of new pediatrics,infection and rehabilitation. There were 138 cases of irrational use of Dexamethasone sodium phosphate injection found in special comment, and the total irrational use rate was 10.84%. The types of irrational use included inappropriate indication（contraindication,59.42%）,inappropriate drug combination（18.84%）,inappropriate drug selection（15.94%）,inappropriate usage and dosage（3.62%）and inappropriate drug dosage forms or drug delivery methods（2.17%）,etc. The irrational use rate of Dexamethasone sodium phosphate injection monthly declined steadily by month from 30.35% in Jul. 2014 to 7.81% in Jun. 2015 through the special comment;then a consensus of 5 points for the drug use formed in our hospital. CONCLUSIONS：There are irrational situations in the clinical use of Dexamethasone sodium phosphate injection in our hospital,especially in the cases of inappropriate indications. The rationality of the drug can be improved by the development of the special comment. This work should continue to be carried out in the future and perfected.

关 键 词：地塞米松磷酸钠注射液 专项点评 合理用药 

分 类 号：R977.1[医药卫生—药品] R969.3[医药卫生—药学]