多中心临床大数据平台建设及深度应用  

Construction and deep application of multi-center clinical big data platform

作　　者：朱立峰[1] 刘淑君 陈德华[2] 乐嘉锦[2] ZHU Lifeng;LIU Shujun;CHEN Dehua;LE Jiajin(Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China;School of Computer Science and Technology, Donghua University, Shanghai 201620, China)

机构地区：[1]上海交通大学医学院附属瑞金医院,上海200025 [2]东华大学计算机科学与技术学院,上海201620

出　　处：《大数据》2018年第3期46-53,共8页Big Data Research

基　　金：上海市科技发展基金资助项目(No.16JC1400802;No.16JC1400803)~~

摘　　要：多中心临床研究是多中心、多学科对同一临床问题开展广泛协作临床研究的主要途径。传统多中心临床研究主要存在样本量偏小和临床科研相对封闭、开放程度不高的问题。为此,结合了新近兴起的大数据与云计算等技术,将物理上分散的各医院临床中心融合成逻辑上统一的临床大数据,构建了多中心临床大数据应用平台。介绍了多中心临床大数据平台的总体框架设计,详细阐述了平台各个子系统,分析了临床大数据平台的深度应用。Multi-center clinical research is the main approach for multi-center, multi-disciplinary, to develop some collaborative clinical researches on the same clinical issues. The traditional multi-center clinical research mainly has the disadvantages that small sample size and the clinical research is relatively closed and the degree of openness is not high. Therefore, the newly emerging technology, such as big data and cloud computing was combined to integrate clinical centers of physically dispersed hospitals into a logical and unified clinical data. On this basis, a multi-center clinical big data application platform was constructed. First, the overall framework of the multi-center clinical big data platform was designed, and then the subsystems of the platform were elaborated in detail. Finally, the deep application of clinical big data platform was introduced.

关 键 词：多中心临床研究 临床大数据分析与挖掘 临床科研随访系统 

分 类 号：TP391[自动化与计算机技术—计算机应用技术]