联合DCE-MRI及FAIR评价子宫肌瘤高强度聚集超声刀治疗前后的应用价值  

Clinical Value of Combined DCE-MRI and FAIR in the Evaluationof High Intensity Focused Ultrasound in the Treatment of Uterine Leiomyoma

作　　者：王习 吴准 王宗英 潘姿璇[2] 王滨 王锡臻[1] WANG Xi;WU Zhun;WANG Zong-ying;PAN Zi-xuan;WANG Bin;WANG Xi-zhen(Image center of Affiliated Hospital of Weifang Medical University;, Gynecology Department of Affiliated Hospital of Weifang Medica University ,Image center of Affiliated Hospital of Weifang Medical University Shandong, Weifang 261035, P.R.C.;Institute of Medical Imaging, Binzhou Medical University)

机构地区：[1]潍坊医学院医学影像学系 [2]潍坊医学院附属医院妇科 [3]滨州医学院医学影像学研究所

出　　处：《中国医学计算机成像杂志》2018年第3期258-261,共4页Chinese Computed Medical Imaging

基　　金：国家自然科学基金项目(81641074;81171303;30470518;81771828);山东省自然科学基金(ZR2009CL046;ZR2010HQ029;ZR2016HL40;ZR2017MH037);山东省优秀中青年科学家科研奖励基金(BS2012YY038);山东省卫生厅科技发展项目(2011WSB29009;2011HW067;2017WS408;2017WS579);滨州医学院山东省特色重点学科;潍坊医学院博士科研启动基金(2009);潍坊医学院大学生科技创新基金(KX2015011;KX2016038;KX2017041);潍坊市科技发展计划项目(2017YX054)~~

摘　　要：目的:探讨流动敏感交互式反转恢复(FAIR)及磁共振动态增强(DCE-MRI)在评估高强度聚焦超声(HIFU)治疗子宫肌瘤的应用价值。方法:23例患者共26个子宫肌瘤于HIFU刀治疗前后行DCE-MRI及磁共振FAIR序列检查。记录并对比HIFU刀治疗前后子宫肌瘤FAIR值、DCE-MRI时间-信号曲线、最大斜率值(MAX Slope)。结果:子宫肌瘤DCE-MRI时间-信号曲线呈持续强化,HIFU治疗后,子宫肌瘤DCE-MRI时间-信号曲线平直,肿瘤无强化,HIFU前后FAIR均值由111.37降为88.55(P<0.05),MAX Slope数值的均值由196.93,降低为100.73,(P<0.05)。结论:FAIR及DCE-MRI均可反映子宫肌瘤HIFU刀治疗前后的血流变化。Purpose： To investigate the value of FAIR and DCE-MRI in assessment of high intensity focused ultrasound （HIFU） in the treatment of uterine leiomyoma. Methods： Twenty-three patients with 26 uterine leiomyomas were included in this study. FAIR and DCE-MRI were performed before and after HIFU treatment. FAIR value, time-intensity curve and maximum slope of uterine leiomyomas before and after HIFU were recorded.Results： The DCE-MRI time-intensity curve of uterine leiomyomas showed continuous enhancement before HIFU. After HIFU treatment, the DCE-MRI time-intensity curve of uterine leiomyoma was straight. The mean FAIR value decreased from 111.37±21.32 to 88.55±27.78 （P 〈0.05） after HIFU. The mean value of maximum slope decreased from 196.93±115.64 to 100.73±104.53 （P〈0.05）. Conclusion： FAIR and DCE-MR/can reflect the blood flow change of uterine leiomyoma before and after HIFU treatment.

关 键 词：子宫肌瘤 高强度聚焦超声 磁共振成像 流动敏感交互式反转恢复序列 动态增强MRI 

分 类 号：R445.1[医药卫生—影像医学与核医学]