异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉与静吸复合麻醉的麻醉效果比较  

Anesthesia effect comparison of target controlled intravenous anesthesia with propofol combined with fentanyl or remifentanil and combination with inhalation anesthesia

作　　者：罗丽[1] LUO Li.(Department of Anesthesiology, Suining Central Hospital, Suining 629000, Chin)

机构地区：[1]四川省遂宁市中心医院麻醉科,629000

出　　处：《临床合理用药杂志》2018年第6期67-68,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的比较异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉与静吸复合麻醉的麻醉效果。方法选取遂宁市中心医院2016年5月—2017年5月收治的行腹腔镜胆囊切除手术患者72例,随机分为观察组A、观察组B和对照组,各24例。观察组A采用异丙酚复合芬太尼靶控静脉麻醉,观察组B采用异丙酚复合瑞芬太尼靶控静脉麻醉,对照组患者采用异丙酚复合芬太尼静吸复合麻醉。比较3组患者睁眼时间、自主呼吸恢复时间、定向能力恢复时间、拔管时间,及术后24 h恶心、呕吐发生率、术后疼痛评分。结果 3组患者睁眼时间、自主呼吸恢复时间、拔管时间比较,差异无统计学意义(P>0.05);观察组A和观察组B定向能力恢复时间短于对照组,恶心呕吐发生率及术后疼痛评分低于对照组(P<0.05)。观察组A和观察组B定向能力恢复时间、恶心呕吐发生率、术后疼痛评分比较,差异无统计学意义(P>0.05)。结论与静吸复合麻醉相比,异丙酚复合芬太尼或瑞芬太尼靶控静脉麻醉后患者定向能力恢复时间较短,恶心呕吐发生率较低,术后疼痛程度较轻,且更为安全、稳定。Objective To compare the anesthesia effect of target controlled intravenous anesthesia with propofol combined with fentanyl or remifentanil and combination with inhalation anesthesia. Methods A total of 72 cases of patients with laparoscopic cholecystectomy resection were selected from May 2016 to May 2017 in Suining Central Hospital,which were randomly divided into observation group A,observation group B and control group,24 cases in each group. The observation group A was given target controlled intravenous anesthesia with propofol combined with fentanyl,observation group B was given target controlled intravenous anesthesia with propofol combined with remifentanil,control group was given inhalation anesthesia with propofol combined with fentanyl. The open eyes time, breathing recovery time, directional ability recovery time, extubation time,the incidence of nausea and vomiting after operation,postoperation pain scores were compared among three groups. Results No statistical differences of open eyes time,breathing recovery time or extubation time was found among three groups（ P〈0. 05）; the observation group A,observation group B of directional ability recovery time were shorter than control group,the incidence rate of nausea and vomiting and postoperation pain scores were lower than control group（ P〈0. 05）. No significant differences of directional ability recovery time,the incidence of nausea and vomiting or postoperation pain scores was found between the observation group A and observation group B（ P〉0. 05）. Conclusion Compared with inhalation combined anesthesia,propofol combined with fentanyl or remifentanil target controlled intravenous anesthesia have shorter directional ability recovery time,lower nausea and vomiting rate and postoperation pain,and with more safety and stable.

关 键 词：异丙酚 芬太尼 瑞芬太尼 靶控静脉 静吸复合 

分 类 号：R614[医药卫生—麻醉学]