Coflex棘突间固定系统治疗退行性腰椎管狭窄症的疗效分析  

作　　者：王雪鹏[1] 李茂强[1] 边振宇[1] 周少波[1] 朱六龙[1] 

机构地区：[1]杭州市第一人民医院,310006

出　　处：《浙江临床医学》2018年第7期1164-1165,共2页Zhejiang Clinical Medical Journal

基　　金：浙江省自然科学基金（LY16H060009）

摘　　要：目的评价Coflex棘突间非融合固定系统治疗退行性腰椎管狭窄症（LSS）的临床疗效。方法选择2012年9月至2014年8月退行性LSS患者22例，于相应狭窄节段减压后将Coflex棘突间固定装置植于L3-4、L4-5或L5～S1棘突间。所有患者随访至少12个月，平均随访时间24个月。在术前、术后分别采用疼痛视觉评分（VAS）、Oswestry功能障碍指数评分（ODI）和Roland-Morris功能障碍问卷（RM）评估患者术后疼痛缓解和功能障碍恢复情况。结果除下肢VAS评分术后第1年和第2年稍有回升，与术前比较差异无统计学意义（P〉0.05），其余腰部VAS评分、ODI指数及RM评分，术后各时间点与术前比较差异有统计学意义（P〈0．05）。结论有限减压后植入棘突间固定装置Coflex治疗退行性LSS短期临床疗效较为满意。Objective To evaluate the clinical efficacy of Coflex interspinous non-fusion fixation system for the treatment of degenerative lumbar spinal stenosis. Methods A total of 22 patients with degenerative lumbar spinal stenosis were treated with Coflex at onr discipline from September 2012 to August 2014. After the corresponding segments were decompressed, the Coflex interspinous devices were implanted into the spinous processes of L3/4, L4/5 or L5/S1. All patients were followed up for at least 12 months, and the average follow-up time was 24 months. Visual analogue scale （ VAS ） , Oswestry disability index （ ODI ） and Roland-Morris Disability Questionnaire （ RM ） were used to evaluate postoperative pain relief and fnnctional recovery before and after operation. Results For VAS-leg score, there was a slight increase in the first and second years after operation.When compared with pre-operation, there were no significant difference at these two time points （ P〉0.05 ） . There were statistically significant differences in the VAS back scores, ODI index and RM score at all the time points post-operation compared to pre-operation （P〈0.05） . Conclusions The short term clinical effect of Coflex is satisfactory in the treatment of degenerative lmnbar spinal canal stenosis after limited decompression.

关 键 词：腰椎管狭窄症 棘突间固定系统 COFLEX 

分 类 号：R681.5[医药卫生—骨科学]