不同腧穴配伍灸法联合美沙拉嗪治疗溃疡性结肠炎的平行对照研究  

Study on the parallel control of different combination of acupoints moxibustion for treatment of ulcerative colitis

作　　者：董雪莲[1] 常玉洁[1] 吴艳红[2] 赵凤玲 张晓蕾[1] DONG Xue - lian;CHANG Yu -jie;WU Yan- hong;ZHAO Feng - lin;ZHANG Xiao - lei(Tangshan City Hospital of traditional Chinese medicine, Hebei Tangshan 063000;Tangshan City Hospital of infec- tious diseases, Hebei Tangshan 063000)

机构地区：[1]唐山市中医医院,河北唐山063000 [2]唐山市传染病医院,河北唐山063000

出　　处：《世界中西医结合杂志》2018年第5期649-652,共4页World Journal of Integrated Traditional and Western Medicine

基　　金：2017年度河北省中医药管理局科学技术课题(2017250)

摘　　要：目的探讨不同腧穴配伍灸法联合美沙拉嗪治疗溃疡性结肠炎的临床有效性及差异性。方法选择溃疡性结肠炎患者105例,随机分为治疗组、对照1组、对照2组,每组35例。3组均给予美沙拉嗪肠溶片治疗,灸法均采用隔药饼灸法,对照1组给予辨证取穴(天枢、大肠俞、足三里、丰隆);对照2组给予子午流注取穴;治疗组给予神阙八阵取穴。观察3组患者治疗前后细胞因子水平、中医症状、大肠黏膜积分变化。结果治疗后治疗组与对照1组、对照2组在细胞因子(Hs-CRP、IL-6、TNF-α)水平、中医症状积分(腹痛、腹泻、脓血便)、大肠黏膜积分方面比较,差异有统计学意义(P<0.05);治疗组、对照1组、对照2组临床疗效总有效率比较差异有统计学意义(P<0.05)。结论神阙八阵取穴灸法联合美沙拉嗪能明显改善溃疡性结肠炎的细胞因子水平及大肠黏膜情况,缓解临床症状,具有明显的优越性。Objective To explore the clinical efficacy and different acupoints compatibility of moxibustion combined with beauty of salad in the treatment of ulcerative colitis. Methods A total of 105 patients with ulcerative colitis were randomly divided into treatment group,control group（ n = 1） and control group（ n = 35）（ n = 2）. The 3 groups were given basic treatment of oral 3/,Mesalazin Enteric-coated Tablets 1 g,are used in herbal cake separated moxibustion moxibustion,the control group was given 1 dialectical acupoints（ Tianshu,Zusanli,Feng Long）; the control group 2 given Ziwuliuzhu acupuncture; the treatment group was given acupoint Shenque eight array. The 3 groups of patients before and after treatment of cytokines,TCM symptoms,change in colorectal mucosal score. Results after treatment,the treatment group and the control group 1 and control group 2 on cytokines（ Hs-CRP,IL-6,TNF-alpha） level,TCM symptoms（ abdominal pain,diarrhea,pus and blood stool）,colorectal mucosa score,there was significant difference（ P〈0. 05）; the treatment group and the control group 1,2 groups of photos the total curative rate were 91. 43%,80%,77. 14%,there was statistically significant difference（ P〈0. 05）. Conclusion Shenque acupoints moxibustion combined with the eight array of salad can significantly improve the level of cytokines in ulcerative colitis and colorectal mucosa,alleviate the clinical symptoms,has obvious superiority.

关 键 词：腧穴配伍 药饼 灸法 溃疡性结肠炎 

分 类 号：R259[医药卫生—中西医结合]