北京市通州区手足口病单次和重复感染者的流行特征分析  

Epidemiological characteristic of single and repeated infection with hand-foot-and-mouth disease( HFMD) in Tongzhou,Beijing

作　　者：李秋虹[1] 李沐 李洪军[1] 陈立新[1] 杨艳娜[1] 郗璐 郑燃燃 LI Qiu - hong;LI Mu;LI Hong - jun;CHEN Li - xin;YANG Yan- na;XI Lu;ZHENG Ran - ran(The Beijing Tongzhou Centers for Disease Control and Prevention,Beijing 100021, China)

机构地区：[1]北京市通州区疾病预防控制中心,北京100021

出　　处：《现代预防医学》2018年第13期2319-2323,共5页Modern Preventive Medicine

摘　　要：目的了解通州区手足口病单次和重复感染者流行病学特征,为防控工作提供科学依据。方法利用中国疾病监测信息系统,整理通州区2008年1月-2017年7月手足口病数据,采用描述性流行病学方法分析单次和重复感染病例的三间分布、临床类型及病原学特征。结果 2008年1月-2017年7月通州区报告手足口病30 090例,重复感染率为4.91%。单次感染和重复感染发病高峰均在5～7月。重复感染间隔时间中位数为404d,84%的重复感染发生在30个月以内。重复感染好发年龄为1～3岁,重复感染者首次感染时散居儿童占63.11%。重复感染人群男女性别比为1.64∶1。重症、轻症病例重复感染率分别为9.86%和4.88%。EV71感染者的重复感染率高于CoxA 16感染者。结论通州区手足口病重复感染高发人群为低龄、男性儿童,首发为重症或EV71感染更易发生重复感染。应加强社区、家庭和流动人口密集地区手足口病健康宣教工作。Objective To study the epidemiological characteristics of single and repeated infection with HFMD in Tongzhou district of Beijing,and to provide a scientific basis for the prevention and control of HFMD in Tongzhou district. Methods Utilizing the National Network for Disease Control and Prevention and Public Health Information System in China,we organized the data of HFDM in Tongzhou district from January 2008 to July 2017 and analyzed the spatial,temporal and population distribution,clinical types and etiological characteristics of single and repeated infection cases by the descriptive epidemiological method. Results 30090 HFMD cases were reported in Tongzhou district of Beijing,and the incidence of repeated infections was 4. 91%. The peaks of single infection and repeated infection were both from May to July. The median interval between repeated infections was 404 d,and 84% of the repeated infections occurred within 30 months. Most of HFMD reinfections cases occurred in children aged 1-3,and the number of scattered children was 63. 11% during the first infection. The sex ratio of male and female in reinfected people was 1. 64 ∶ 1. The repeated infection rates in severe and mild cases were 9. 86% and 4.88%,respectively,and those with EV71 infection was higher than those with Cox A16 infection. Conclusion The people with a high incidence of HFMD repeated infection in Tongzhou District is low age,male children. The primary infection is severe or EV71 infection cases are more likely to repeat infection. Health education for HFMD should be strengthened in communities,families and densely populated areas.

关 键 词：手足口病 重复感染 流行病学 病原学 

分 类 号：R181.23[医药卫生—流行病学]