从东西方种族差异看缺血性卒中抗血小板治疗策略选择  

Strategy Selection of Antiplatelet Therapy for Ischemic Stroke in terms of the Ethnic Differences between Easterners and Westerners

作　　者：王伊龙[1] Wang Yi-Long(Neurology Central, Beijing Tiantan Hospital, Capital Medical Universit;National Clinical Research Center for Neurological Diseases, Beijing 100050, Chin)

机构地区：[1]首都医科大学附属北京天坛医院神经病学中心国家神经系统疾病临床医学研究中心,北京100050

出　　处：《中国卒中杂志》2018年第5期494-499,共6页Chinese Journal of Stroke

基　　金：国家科技支撑计划(2015BAI12B04;2015BAI12B02);国家重点研发计划(2016YFC0901000;2016YFC0901001;2016YFC0901002;2017YFC1307900)

摘　　要：全球卒中的疾病负担沉重,抗血小板治疗是缺血性卒中二级预防的必要手段,然而东西方人群的疾病特点存在差异,可能对抗血小板治疗的选择产生影响。本综述从卒中发病特点、患者复发和出血风险差异以及抗血小板治疗反应多样性等多角度出发,探讨适合亚洲人群的缺血性卒中抗血小板治疗方案。Stroke has become a global disease burden.Antiplatelet therapy is a necessary method for secondary prevention of ischemic stroke.However,there are differences between Easterners and Westerners on features of disease,which may lead to different antiplatelet therapy.Through the analysis of difference in disease characteristics,risk of recurrence and bleeding,and variability of platelet response,this review will explore the appropriate antiplatelet therapy for ischemic stroke patients in Asia.

关 键 词：卒中 抗血小板药物 二级预防 基因多态性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]