复方血栓通胶囊联合曲安奈德球后注射辅助全视网膜光凝治疗糖尿病黄斑水肿疗效分析  

Effect of Fufang Xueshuantong capsule and triamcinolone acetonide retrobulbar injection combine with panretinal photocoagulation for diabetic macular edema

作　　者：吴香丽[1] 谢赟[2] 殷英霞[1] 陈建华[1] 刘彦[1] 赵慧英[1] 陈冬军[1] Wu Xiangli;Xie Yun;Yin Yingxia(Department of Ophthalmology,Beijing Geriatrics Hospital（Beijing100095)

机构地区：[1]北京老年医院眼科,北京100095 [2]河北省疾病预防控制中心,石家庄050021

出　　处：《陕西中医》2018年第6期736-738,共3页Shaanxi Journal of Traditional Chinese Medicine

摘　　要：目的:探讨复方血栓通联合曲安奈德(TA)球后注射辅助全视网膜光凝(PRP)治疗糖尿病黄斑水肿(DME)的疗效。方法:收集重度非增殖期糖尿病视网膜病变合并DME患者51例(60眼),据DME轻、中、重程度分三组,1组19眼,2组18眼,3组23眼。3组患者行PRP前3天球后注射TA,并应用复方血栓通胶囊1.5g,3次/d,应用1个月。分4次完成PRP,1个月及3个月复查。观察三组患者治疗前后最佳矫正视力(BCVA)、视网膜厚度(RT)、黄斑中心区视网膜厚度(MFRT)及并发症,3个月时行荧光素血管造影(FFA)检查。结果:1组及2组治疗后1个月及3个月BCVA及RT均较治疗前差异有统计学意义(P<0.05);3组治疗后1月BCVA及MFRT较治疗前差异有统计学意义(P<0.05),3个月BCVA及MFRT较治疗前差异无统计学意义(P>0.05)。3个月时行FFA,1组4眼,2组6眼,3组21眼补激光治疗,差异均有统计学意义(P<0.05)。三组均未出现并发症。结论:复方血栓通联合TA球后注射辅助全视网膜光凝(PRP)治疗轻中度DME可以达到较好的治疗效果,安全无并发症。Objective：To investigate the Fufang Xueshuantong capsule（FXST）and triamcinolone acetonide retrobulbar injection combine with panretinal photocoagulation（PRP）for the treatment of diabetic macular edema（DME）.Methods：People with non proliferation diabetic retinopathy combined DME 51 cases（60 eyes）,divided into3 groups,according to the degree of DME.19 eyes of group 1,18 eyes of group 2,23 eyes of group 3.3 days before the PRP,three groups of patients were injection of TA,and received FXST orally 1.5 g 3 times per day for one month,four times to complete the PRP.To observed patients with BCVA,RT,MFRT and its complications in 1 mo and 3 mo,fluorescein angiography（FFA）was observed.Results：the BCVA and RT of 1 and 2 groups after treatment was improved in 1 mo and 3 mo and the difference was statistical significance（P〈0.05）;the BCVA and MFRT of the 3 group was improved in 1 mo and the difference was statistically significant（P〈0.05）,but the BCVA and MFRT was no statistically significant difference in 3 mo（P〈0.05）.FFA on 3 mo,4 eyes of 1 group,6 eyes of 2 group,21 eyes of 3 group need to laser treatment again,differences were statistically significant（P〈0.05）.All patients with no complications.Conclusion：FXST and triamcinolone acetonide retrobulbar injection combine with panretinal photocoagulation（PRP）treatment of little and moderate DME can achieve a better therapeutic effect and safety without complications.

关 键 词：糖尿病并发症 黄斑水肿/中西医结合疗法 @复方血栓通胶囊 

分 类 号：R587.2[医药卫生—内分泌]