乐托尔联合神经节甘酯治疗婴幼儿轮状病毒肠炎合并脑炎的疗效及机制探讨  

The therapeutic effect and mechanism of letol ganglion combined with encephalitis in the treatment of infant rotavirus enteritis

作　　者：刘杰[1] 王中柱[1] LIU Jie;WANG Zhongzhu(Department of Paediatrics,Huangshi Central Hospital of E Dong Group,Huangshi 435100,Hubei,China)

机构地区：[1]鄂东医疗集团黄石市中心医院儿科,湖北黄石435100

出　　处：《中南医学科学杂志》2018年第3期299-301,共3页Medical Science Journal of Central South China

摘　　要：为探讨乐托尔联合神经节甘酯治疗婴幼儿轮状病毒肠炎合并脑炎的疗效及对炎症因子的影响,选择60例轮状病毒肠炎合并脑炎婴幼儿患者作为研究对象,采用乐托尔联合神经节甘酯治疗,观察患者的临床疗效和不良反应发生情况,以及炎症因子的水平变化情况。结果显示,乐托尔联合神经节甘酯能显著改善患者疗效,且炎症因子MCP-1水平、TNF-α水平和IL-6水平显著低于常规治疗组水平。乐托尔联合神经节甘酯治疗婴幼儿轮状病毒肠炎合并脑炎疗效显著,不良反应低,其机制可能与降低患者炎症因子水平有关。To investigate the effect of lotol combined with gangliolide in the treatment of infantile rotavirus enteritis with encephalitis and its effect on inflammatory factors. 60 cases of Rotavirus Enteritis Complicated with encephalitis in our hospital were selected as the subjects. The clinical effects and adverse reactions were observed,and the levels of the inflammatory factors were analyzed. Results showed that the efficacy of lotorol combined with ganglionic acid in the treatment of infantile rotavirus enteritis associated with encephalitis is significant,with low side effects,and it can also reduce the level of inflammatory factors,which is worthy of clinical promotion.

关 键 词：乐托尔 神经节甘酯 婴幼儿轮状病毒肠炎 脑炎 炎症因子 

分 类 号：R725.9[医药卫生—儿科]