药物洗脱支架与冠状动脉旁路移植术治疗多支冠状动脉病变的临床效果对比分析  

Comparative analysis of clinical effects of drug-eluting stents and coronary artery bypass grafting in the treatment of multiple coronary artery lesions

作　　者：张海[1] 曹勇[1] 胡楝[1] 魏芝宝[1] 陈海坚[1] 朱秀龙[1] ZHANG Hai;CAO Yong;HU Lian;WEI Zhibao;CHEN Haijian;ZHU Xiulong(Department of Cardiovascular Surgery,District 1,Gaozhou People＇s Hospital,Guangdong Province,Gaozhou 525200,China)

机构地区：[1]广东省高州市人民医院心血管外科一区,广东高州525200

出　　处：《中国医药科学》2018年第9期214-217,共4页China Medicine And Pharmacy

摘　　要：目的探讨药物洗脱支架与冠状动脉旁路移植术治疗多支冠状动脉病变的疗效情况。方法分析我院2014年1月~2017年12月收治的300例多支冠状动脉病变患者临床资料,依据治疗方式不同进行分组,DES组150例和CABG组150例,术后随访10个月。观察两组多支冠状动脉病变患者临床治疗结果和随访情况。结果 CABG组多支冠状动脉病变患者术后住院时间高于DES组,差异有统计学意义(P<0.05)。两组患者总死亡率、急性心肌梗死、非致死性心肌梗死、脑血管疾患、再次血运重建率、MACCE差异均无统计学意义(P>0.05)。术后随访情况,CABG组多支冠状动脉病变患者再次血运重建率低于DES组,差异有统计学意义(P<0.05);两组患者总死亡率、非致死性心肌梗死、脑血管疾患、MACCE差异均无统计学意义(P>0.05)。结论冠状动脉旁路移植术治疗多支冠状动脉病变患者,再次血运重建率低,预后良好,值得临床推广应用。Objective To investigate the efficacy of drug-eluting stents and coronary artery bypass grafting in the treatment of multiple coronary artery lesions. Methods The clinical data of 300 patients with multiple coronary artery disease admitted to our hospital from January 2014 to December 2017 were analyzed.According to the different treatment methods,150 cases in des group and 150 cases in CABG group were divided into two groups,followed up for 10 months.The clinical outcome and follow-up of two groups of patients with multiple coronary artery lesions were observed. Results In group CABG,the postoperative hospitalization time of patients with multiple coronary artery lesions was higher than that of group DES,the difference was statistically significant（P〈0.05）.There was no statistically significant difference in total mortality,acute myocardial infarction,non-fatal myocardial infarction,cerebrovascular diseases,revascularization rate and macce between the two groups（P〉0.05）.After operation,the revascularization rate of patients with multiple coronary artery lesions in group CABG was lower than that in group DES,and the difference was statistically significant（P〈0.05）. There was no statistically signficant difference in total mortality, non-fatal myocardial infarction, cerebrovascular disease, and MACCE between the two groups（P〉0.05）.Conclusion Coronary artery bypass grafting in the treatment of patients with multiple coronary artery lesions has low revascularization rate and good prognosis,which is worthy of clinical popularization and application.

关 键 词：药物洗脱支架 冠状动脉旁路移植术 多支冠状动脉病变 急性心肌梗死 再次血运重建率 

分 类 号：R541.4[医药卫生—心血管疾病]