宫颈环切术中应用阿替卡因肾上腺素注射液的临床疗效观察  

Observation on the clinical efficacy of articaine hydrochloride and epinephrine tartrate injection in the cervical circumcision

作　　者：何庆华 昌大平 HE Qinghua;CHANG Daping(Jiangmen Jianghai People＇s Hospital,Jiangmen 529080,Chin)

机构地区：[1]广东省江门市江海区人民医院,广东江门529080

出　　处：《中国医药科学》2018年第10期45-47,共3页China Medicine And Pharmacy

摘　　要：目的探析宫颈环切术中应用阿替卡因肾上腺素注射液(必兰)的临床疗效。方法选取2016年10月~2017年9月在我院行宫颈环切术治疗的100例患者为研究对象,经我院医学伦理委员会批准通过后采用随机分配原则分组,每组50例。对照组不采用任何药物,观察组采用阿替卡因肾上腺素注射液(必兰),对两组的术中术后的宫颈出血量、术中用时、术后伤口愈合的情况、术后阴道排液量及持续时间、安全性进行对比分析。结果 (1)观察组患者的术中出血量、术后失血量、手术时间明显少于对照组,组间对比差异有统计学意义(P<0.05);(2)观察组患者的术后阴道排液量和术后阴道排液持续时间均明显优于对照组,两组差异有统计学意义(P<0.05);(3)观察组患者的术后伤口愈合时间、不良反应发生率明显优于对照组,两组差异有统计学意义(P<0.05)。结论行宫颈环切术患者使用阿替卡因肾上腺素注射液,可更好地减少出血量,充分暴露手术视野,缩短手术时间,更有利于术后伤口愈合,且安全性更高,值得在临床上进一步推广应用。Objective To investigate the clinical efficacy of articaine hydrochloride and epinephrine tartrate injection in cervical circumcision. Methods One hundred cases of cervical circumcision in our hospital from October 2016 to September 2017 were selected as research subjects.After the approval of the medical ethics committee of our hospital,50 cases were randomly assigned to each group.The control group did not use any drugs,the observation group adopted articaine hydrochloride and epinephrine tartrate injection.The two groups of postoperative cervical bleeding,intraoperative time,postoperative wound healing,postoperative vaginal discharge,duration and safety were compared and analyzed. Results（1）The intraoperative blood loss, postoperative blood loss and operative time in the observation group were significantly less than those in the control group,and the difference between the two groups was statistically significant（P〈0.05）.（2）The amount of vaginal discharge and the duration of postoperative vaginal discharge in the observation group were significantly better than those in the control group,and the difference between the two groups was statistically significant（P〈0.05）.（3）The wound healing time and incidence of adverse reactions in the observation group were significantly better than those in the control group,and the difference between the two groups was statistically significant（P〈0.05）. Conclusion The use of articaine hydrochloride and epinephrine tartrate injection in cervical circumcision can better reduce the amount of bleeding,fully expose the visual field,shorten the operation time,and be more conducive to postoperative wound healing,and it is more safe and worthy of further application in clinical.

关 键 词：宫颈环切术 阿替卡因肾上腺素注射液(必兰) 临床疗效 

分 类 号：R713[医药卫生—妇产科学]