2012～2016年山西省围产儿神经管畸形监测分析  

Monitoring and analysis of neural tube defects among perinatals in Shanxi Province between 2012 and 2016

作　　者：李泽红 黄晶[1] 李玉凤[1] 陈东方[1] LI Ze-hong;HUANG Jing;LI Yu-feng;CHEN Dong-fang(Shanxi maternity and child health care hospital, Taiyuan 030013)

机构地区：[1]山西省妇幼保健院,太原030013

出　　处：《中国优生与遗传杂志》2018年第6期90-91,69,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨2012~2016年山西省围产儿神经管畸形的患病特征,为下一步的预防干预措施提供依据。方法采用以医院监测为基础监测的监测方案,监测对象为在监测医院内出生的妊娠满28周至出生后7天的围产儿。结果山西省2012~2016年神经管畸形的发生率为8.33/万,呈下降趋势(P<0.05);神经管畸形类型发生顺位由高到低为脊柱裂、脑膨出、无脑儿;男女性发生率无显著差异(P>0.05);农村发生率高于城市(P<0.05);不同年龄组孕母子代神经管畸形的发生率不同(P<0.05),孕母年龄小于25岁和大于35岁子代神经管畸形的发生率较高。结论五年来山西省神经管畸形发生率呈下降趋势,农村地区和低龄产妇的神经管畸形高发应引起重视。Objective：The study aimed to find out the stigmas of neural tube defects from 2012 to 2016 in Shanxi Province,provide basis for the next step of secondary prevention work. Methods：The data was collected from Birth defects monitoring program in Shanxi Province. Perinatals between 28 weeks of gestation and 7 days after birth delivered in monitoring hospitals. Results：The overall prevalence of neural tube defects was 0.833‰,the incidence of neural tube defects downward trend year by year（P〈0.05）;the highest to lowest incidences of neural tube defects were rachischisis,encephalocele,and anencephalus;there was no significant difference in the incidence of male and female;the incidence among rural area was obviously higher than that of urban area（P〈0.05）;In terms of incidence of neural tube defects among the offspring,the higher was in the group of women aged less than 25 years and in the group of women aged more than 35 years,the difference of which was statistically significant（P〈0.05）. Conclusion：The incidence of neural tube defects downward trend year by year during five years. Should be pay attention to the high level of rural area and young women.

关 键 词：神经管畸形 监测 发生率 

分 类 号：R726.2[医药卫生—儿科]