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作 者:刘丽梅[1] 陈曦[1] 岳广欣[1] 柏冬[1] 刘振丽[1] 王淳[1] 张俊华[2] 王瑞海[1] 宋志前[1] 苗青[1] LIU Li-mei;CHEN Xi;YUE Guang-xin;BAI Dong;LIU Zhen-li;WANG Chun;ZHANG Jun-hua;WANG Rui-hai;SONG Zhi-qian;MIAO Qing(Institute of Basic Theory of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China;Institute of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China)
机构地区:[1]中国中医科学院中医基础理论研究所,北京100700 [2]天津中医药大学中医药研究院,天津300193
出 处:《中草药》2018年第11期2489-2495,共7页Chinese Traditional and Herbal Drugs
基 金:国家重点基础研究计划("973")项目(2012CB518401)
摘 要:"中药组分"是组分中药研究中涉及到的核心概念之一,其与"有效成分""有效部位""提取物"概念的异同等问题是开展组分中药研究首先要解决的问题。通过对1999—2017年有关中药组分的期刊文献进行研究,尝试对中药组分的概念涵义进行界定,认为中药组分是组分配伍的基本单元,其来源于有效部位或部位群,是具有较高同质性的成分群或具有一定比例的组合物,其化学成分可识别,且各成分比例相对固定,其活性一般可表征并可重复。同时探讨了中药组分与相关或类似概念的区别与联系,以期得到同道的争鸣,推动组分中药的深入研究。"Chinese materia medica component" is one of the core concepts involved in the study of component-based Chinese medicine. The difference and connection among concepts of "Chinese materia medica component", "active ingredients", "active parts", and "extracts" are the first issue to be solved in the study of component-based Chinese medicine. According to the literature about Chinese materia medica components from 1999 to 2017, we try to define its concept. Chinese materia medica component is the basic unit of component compatibility, which comes from the effective part(s), and it is a group of components with high homogeneity or a certain proportion of the composition. Its chemical composition can be identified, and the proportion of each component is relatively fixed, and its activity is generally characterized and repeatable. Chinese materia medica components, active ingredients, effective parts, and extracts are all different forms of describing the efficacy substances of traditional Chinese medicines. The difference and connection between Chinese materia medica components and related concepts were also discussed. Hence, we hope that the results of this study may provide a reference for the researchers and experts in order to promote the further development of component-based Chinese medicine.
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