基于文本挖掘方法对比2005年前后高血压病“证-法-方药”差异  

Contrasting Differences of “Pattern-Therapeutically Principle-Formula” of Hypertension in This Decade: A Text Mining Analysis

作　　者：李立[1] 郑光[2] 王耀献[3] 杜雅薇[4] 周红梅[4] 崔赵丽[4] 赵雨坤 陈则旭 韩森 姜淼[1] 丁治国[3] LI Li;ZHENG Guang;WANG Yaoxian;DU Yawei;ZHOU Hongmei;CUI Zhaoli;ZHAO Yukun;CHEN Zexu;HAN Sen;JIANG Miao;DING Zhiguo(Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China;School of Information Science and Engineering Technology ,Lanzhou University, Lanzhou 730000, Gansu, China;Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China;Department of Surgery, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China;Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China)

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]兰州大学信息学院,甘肃兰州730000 [3]北京中医药大学东直门医院东区,北京101100 [4]北京中医药大学东直门医院,北京100700 [5]中国中医科学院基础理论研究所,北京100700

出　　处：《辽宁中医杂志》2018年第5期905-908,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金青年项目(81503388,81473367);北京市科技计划课题资助项目(Z121100000312006)

摘　　要：目的：总结近十年高血压病＂证-法-方药＂的诊治规律变化趋势。方法：运用基于敏感关键词频数统计的数据分层算法,以高血压为关键词,分别挖掘2005年前后的相关文献,经过数据挖掘、清洗、可视化等处理,分析近十年前后高血压病常见证候、治法和方药的差异。结果：高血压病的主要证候在2005年前后无明显变化,均以阴虚、肝阳、血瘀为主,次要证候中2005年以前常见血热、肾虚,但在2005年之后,痰瘀、湿热证较多见;高血压病的主要治法在2005年前后无明显变化,均以利尿、活血、补气为主,2005年之前活血通络法,补肾法较多见,而2005年之后化痰法,清热解毒法较为常见;高血压病的常用方药多为天麻钩藤饮、六味地黄汤、补阳还五汤等,在2005之前常用血府逐瘀汤、真武汤,2005之后半夏白术天麻汤、温胆汤更为常用。结论：近十年,高血压病基本＂证-法-方药＂没有发生根本变化,但针对＂痰湿证-化痰祛湿-半夏白术天麻汤＂的诊疗越发受到关注。Objective： To compare the differences of ＂Pattern-Therapeutically principle-Formula＂of Chinese medicine on hypertension in this decade by a text mining analysis. Methods： All literature about hypertension was collected from Sino Med database. The relationships among patterns,therapeutically principles and formulae of hypertension before and after 2005 were studied by data slicing algorithm. The results were shown in frequency tables and 2-dimention networks. Results： There were no obvious differences in mainly patterns,therapeutically principles or formulae of hypertension before and after 2005. However,for the secondary patterns,therapeutically principles and formulae,the frequency of damp-phlegm pattern,resolving phlegm and eliminating dampness and Banxia Baizhu Tianma Decoction were increased in this decade. Conclusion： Diagnosis and treatment of hypertension focus more on＂damp-phlegm pattern-resolving phlegm and eliminating dampness-Banxia Baizhu Tianma Decoction＂in over a decade.

关 键 词：高血压 文本挖掘 证候 治法 方药 

分 类 号：R259.441[医药卫生—中西医结合]